Targeting integrated epigenetic and metabolic pathways in lethal childhood PFA ependymomas
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DOI: 10.1126/scitranslmed.abc0497
Abstract: Description Childhood posterior fossa group A ependymomas demonstrate integrated metabolic and epigenetic pathways that can be disrupted by metformin. Understanding childhood ependymomas Children with posterior fossa group A (PFA) ependymomas have a dismal prognosis. PFAs… read more here.
Keywords: childhood; tca cycle; cycle metabolism; ezhip ... See more keywords