Pharmacotherapy of retinal disease with visual cycle modulators
Sign Up to like & getrecommendations! Published in 2018 at "Expert Opinion on Pharmacotherapy"
DOI: 10.1080/14656566.2018.1448060
Abstract: ABSTRACT Introduction: Pharmacotherapy with visual cycle modulators (VCMs) is under investigation for retinitis pigmentosa (RP), Leber congenital amaurosis (LCA), Stargardt macular dystrophy (SMD) and nonexudative age-related macular degeneration (AMD), all blinding diseases that lack effective… read more here.
Keywords: vcms; pharmacotherapy retinal; retinal disease; visual cycle ... See more keywords
Identifying Cell Cycle Modulators That Selectively Target ARID1A Deficiency Using High-Throughput Image-Based Screening
Sign Up to like & getrecommendations! Published in 2017 at "SLAS Discovery"
DOI: 10.1177/2472555217698942
Abstract: ARID1A, a component of the chromatin remodeling complex SWI/SNF, is an evolutionarily conserved complex that uses the energy of adenosine triphosphate hydrolysis to remodel chromatin structure and functions as a master regulator of gene transcription.… read more here.
Keywords: cell cycle; target arid1a; cell; selectively target ... See more keywords