Novel coumarin- and quinolinone-based polycycles as cell division cycle 25-A and -C phosphatases inhibitors induce proliferation arrest and apoptosis in cancer cells.
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DOI: 10.1016/j.ejmech.2017.04.012
Abstract: Cell division cycle phosphatases CDC25 A, B and C are involved in modulating cell cycle processes and are found overexpressed in a large panel of cancer typology. Here, we describe the development of two novel… read more here.
Keywords: cycle phosphatases; cell division; cancer; division cycle ... See more keywords