The prolyl hydroxylase OGFOD1 promotes cancer cell proliferation by regulating the expression of cell cycle regulators
Sign Up to like & getrecommendations! Published in 2022 at "FEBS Letters"
DOI: 10.1002/1873-3468.14547
Abstract: OGFOD1, a prolyl‐hydroxylase, has been reported to translocate from the nucleus to the cytoplasm in response to cellular stress. Here, we demonstrate that OGFOD1 regulates the transcription and post‐transcriptional stabilization of cell cycle‐related genes. OGFOD1… read more here.
Keywords: cell; prolyl hydroxylase; cell cycle; cycle regulators ... See more keywords
Effect of tricarboxylic acid cycle regulators on the formation of humic substance during composting: The performance in labile and refractory materials.
Sign Up to like & getrecommendations! Published in 2019 at "Bioresource technology"
DOI: 10.1016/j.biortech.2019.121949
Abstract: The aims of this study are to reveal the roles of tricarboxylic acid (TCA) cycle regulators in reducing CO2 emission and promoting humic substance (HS) formation during composting with different materials. The results showed that… read more here.
Keywords: humic substance; tricarboxylic acid; cycle regulators; co2 emission ... See more keywords
A quantitative and spatial analysis of cell cycle regulators during the fission yeast cycle
Sign Up to like & getrecommendations! Published in 2022 at "Proceedings of the National Academy of Sciences of the United States of America"
DOI: 10.1073/pnas.2206172119
Abstract: We have carried out a systems-level analysis of the spatial and temporal dynamics of cell cycle regulators in the fission yeast Schizosaccharomyces pombe. In a comprehensive single cell analysis we have precisely quantified the levels… read more here.
Keywords: cell; cycle; cell cycle; cycle regulators ... See more keywords
Effect of Triptolide on Temporal Expression of Cell Cycle Regulators During Cardiac Hypertrophy
Sign Up to like & getrecommendations! Published in 2020 at "Frontiers in Pharmacology"
DOI: 10.3389/fphar.2020.566938
Abstract: Adult mammalian cardiomyocytes may reenter the cell cycle and cause cardiac hypertrophy. Triptolide (TP) can regulate the expressions of various cell cycle regulators in cancer cells. However, its effects on cell cycle regulators during myocardial… read more here.
Keywords: cycle regulators; hypertrophy; expression; cell cycle ... See more keywords
Identification of Novel Drugs Targeting Cell Cycle Regulators for the Treatment of High-Grade Serous Ovarian Cancer via Integrated Bioinformatics Analysis
Sign Up to like & getrecommendations! Published in 2022 at "Symmetry"
DOI: 10.3390/sym14071403
Abstract: High-grade serous ovarian carcinoma (HGSC), the most common and aggressive histological type of ovarian cancer, remains the leading cause of cancer-related deaths among females. It is important to develop novel drugs to improve the therapeutic… read more here.
Keywords: cell; cell cycle; cycle regulators; treatment ... See more keywords
BCL-XL blockage in TNBC models confers vulnerability to inhibition of specific cell cycle regulators
Sign Up to like & getrecommendations! Published in 2021 at "Theranostics"
DOI: 10.7150/thno.60503
Abstract: Cell cycle regulators are frequently altered in Triple-Negative Breast Cancer (TNBC). Emerging agents targeting these signals offer the possibility to design new combinatorial therapies. However, preclinical models that recapitulate TNBC primary resistance and heterogeneity are… read more here.
Keywords: cell cycle; vulnerability; tnbc; cycle regulators ... See more keywords
Convergent recruitment of TALE homeodomain life cycle regulators to direct sporophyte development in land plants and brown algae
Sign Up to like & getrecommendations! Published in 2019 at "eLife"
DOI: 10.7554/elife.43101
Abstract: Three amino acid loop extension homeodomain transcription factors (TALE HD TFs) act as life cycle regulators in green algae and land plants. In mosses these regulators are required for the deployment of the sporophyte developmental… read more here.
Keywords: tale; sporophyte; cycle regulators; life ... See more keywords