Local nuclear to cytoplasmic ratio regulates H3.3 incorporation via cell cycle state during zygotic genome activation
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DOI: 10.1038/s44319-025-00596-1
Abstract: Early embryos often have unique chromatin states prior to zygotic genome activation (ZGA). In Drosophila, ZGA occurs after 13 reductive nuclear divisions during which the nuclear to cytoplasmic (N/C) ratio grows exponentially. Previous work found… read more here.
Keywords: incorporation; cell cycle; cell; ratio ... See more keywords
Inhibited KdpFABC transitions into an E1 off-cycle state
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DOI: 10.7554/elife.80988
Abstract: KdpFABC is a high-affinity prokaryotic K+ uptake system that forms a functional chimera between a channel-like subunit (KdpA) and a P-type ATPase (KdpB). At high K+ levels, KdpFABC needs to be inhibited to prevent excessive… read more here.
Keywords: cycle; state; type atpase; inhibited kdpfabc ... See more keywords