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Sleep and wake cycles dynamically modulate hippocampal inhibitory synaptic plasticity

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Published in 2022 at "PLOS Biology"

DOI: 10.1371/journal.pbio.3001812

Abstract: Sleep is an essential process that consolidates memories by modulating synapses through poorly understood mechanisms. Here, we report that GABAergic synapses in hippocampal CA1 pyramidal neurons undergo daily rhythmic alterations. Specifically, wake inhibits phasic inhibition,… read more here.

Keywords: sleep wake; wake; plasticity; inhibitory ... See more keywords