The modulatory effects of luteolin on cyclic AMP/Ciliary neurotrophic factor signaling pathway in experimentally induced autoimmune encephalomyelitis
Sign Up to like & getrecommendations! Published in 2019 at "IUBMB Life"
DOI: 10.1002/iub.2099
Abstract: Multiple sclerosis (MS) is considered to be an autoimmune disorder of the central nervous system (CNS) manifested by chronic inflammation. Although its etiology is not completely understood, inflammation and apoptosis are known to be major… read more here.
Keywords: cyclic amp; eae group; group; effects luteolin ... See more keywords
Cyclic AMP does double duty to support parallel signaling in primary cilium and cytosol.
Sign Up to like & getrecommendations! Published in 2021 at "Cell calcium"
DOI: 10.1016/j.ceca.2021.102436
Abstract: The primary cilium maintains all of the necessary machinery to generate and interpret cAMP signals within its tiny volume, leading to the supposition that ciliary cAMP provides unique biological instructions separate from those derived from… read more here.
Keywords: cilium; cyclic amp; amp double; duty support ... See more keywords
The 14-3-3 protein is an essential component of cyclic AMP signaling for regulation of chemotaxis and development in Dictyostelium.
Sign Up to like & getrecommendations! Published in 2020 at "Cellular signalling"
DOI: 10.1016/j.cellsig.2020.109739
Abstract: The evolutionarily-conserved 14-3-3 proteins regulate many cellular processes through binding to various phosphorylated targets in eukaryotes. It first appears in Dictyostelium, however its role in this organism is poorly understood. Here we show that down-regulation… read more here.
Keywords: dictyostelium; cyclic amp; component cyclic; regulation ... See more keywords
A novel reporter system for cyclic AMP mediated gene expression in mammalian cells based on synthetic transgene expression system.
Sign Up to like & getrecommendations! Published in 2019 at "European journal of pharmacology"
DOI: 10.1016/j.ejphar.2019.04.037
Abstract: Cyclic AMP (cAMP) is an important second messenger that mediates various biological functions in both prokaryotes and eukaryotes. Due to the ever increasing significance in studying the function and modulation of cAMP-based signaling, it is… read more here.
Keywords: camp; system; cyclic amp; gene expression ... See more keywords
Cyclic di-AMP: Small molecule with big roles in bacteria.
Sign Up to like & getrecommendations! Published in 2021 at "Microbial pathogenesis"
DOI: 10.1016/j.micpath.2021.105264
Abstract: Cyclic dinucleotides are second messengers that are present in all the three domains of life, bacteria, archaea, and eukaryotes. These dinucleotides have important physiological and pathophysiological roles in bacteria. Cyclic di-AMP (cdA) is one of… read more here.
Keywords: bacteria cyclic; cyclic amp; amp small; small molecule ... See more keywords
In Vivo Detection of Cyclic-di-AMP in Staphylococcus aureus
Sign Up to like & getrecommendations! Published in 2022 at "ACS Omega"
DOI: 10.1021/acsomega.2c04538
Abstract: Cyclic-di-AMP (CDA) is a signaling molecule that controls various cellular functions including antibiotic tolerance and osmoregulation in Staphylococcus aureus. In this study, we developed a novel biosensor (bsuO P6-4) for in-vivo detection of CDA in… read more here.
Keywords: cyclic amp; staphylococcus aureus; aureus; vivo detection ... See more keywords
Protein kinase enzymes in the human vagina—relation to key mediators of the cyclic AMP and cyclic GMP pathways
Sign Up to like & getrecommendations! Published in 2017 at "International Journal of Impotence Research"
DOI: 10.1038/ijir.2017.8
Abstract: Aside from phosphodiesterase (PDE) isoenzymes, protein kinases (cAK=cyclic AMP-binding protein kinase, cGK=cyclic GMP-binding protein kinase) have also been identified as important receptors for cyclic nucleotides. A significance of protein kinases in the control of the… read more here.
Keywords: cyclic amp; cak; relation; cyclic gmp ... See more keywords
Cyclic AMP links luteinizing hormone signaling to dephosphorylation and inactivation of the NPR2 guanylyl cyclase in ovarian folliclesâ€
Sign Up to like & getrecommendations! Published in 2021 at "Biology of Reproduction"
DOI: 10.1093/biolre/ioab029
Abstract: Summary sentence Cyclic AMP elevation links luteinizing hormone receptor signaling to dephosphorylation and inactivation of the NPR2 guanylyl cyclase in preovulatory mouse follicles. read more here.
Keywords: luteinizing hormone; cyclic amp; inactivation npr2; links luteinizing ... See more keywords
Cyclic di-AMP-mediated interaction between Mycobacterium tuberculosis &Dgr;cnpB and macrophages implicates a novel strategy for improving BCG vaccination
Sign Up to like & getrecommendations! Published in 2018 at "Pathogens and Disease"
DOI: 10.1093/femspd/fty008
Abstract: Cyclic di-AMP (c-di-AMP) has been shown to play an important role in bacterial physiology and pathogen-host interactions. We previously reported that deletion of the sole c-di-AMP phosphodiesterase-encoding gene (cnpB) in Mycobacterium tuberculosis (Mtb) led to… read more here.
Keywords: bcg vaccination; cyclic amp; amp; cnpb ... See more keywords
Cyclic-di-AMP signalling in lactic acid bacteria.
Sign Up to like & getrecommendations! Published in 2023 at "FEMS microbiology reviews"
DOI: 10.1093/femsre/fuad025
Abstract: Cyclic-di-AMP is a nucleotide second messenger present in Gram-positive bacteria and some Gram-negative bacteria and Archaea. The intracellular concentration of cyclic-di-AMP is adjusted in response to environmental and cellular cues, primarily through the activities of… read more here.
Keywords: cyclic amp; acid bacteria; acid; lactic acid ... See more keywords
Cyclic di-AMP, a second messenger of primary importance: tertiary structures and binding mechanisms.
Sign Up to like & getrecommendations! Published in 2020 at "Nucleic acids research"
DOI: 10.1093/nar/gkaa112
Abstract: Cyclic diadenylate (c-di-AMP) is a widespread second messenger in bacteria and archaea that is involved in the maintenance of osmotic pressure, response to DNA damage, and control of central metabolism, biofilm formation, acid stress resistance,… read more here.
Keywords: primary importance; tertiary structures; second messenger; cyclic amp ... See more keywords