Chiral phosphoric acid catalyzed aza-Friedel-Crafts alkylation of indoles with cyclic aryl α-ketimino esters
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DOI: 10.1016/j.tetlet.2016.12.012
Abstract: Abstract A highly enantioselective aza-Friedel-Crafts alkylation of indoles with cyclic aryl α-ketimino esters catalyzed by a chiral phosphoric acid has been developed, the corresponding α,α-disubstituted unnatural α-amino ester derivatives were obtained in moderate to high… read more here.
Keywords: crafts alkylation; cyclic aryl; indoles cyclic; alkylation indoles ... See more keywords
Synthesis of Cyclic 3-Aryl-Substituted 1,2-Dicarbonyl Compounds via Suzuki Cross-Coupling Reactions
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DOI: 10.1055/s-0036-1591543
Abstract: A method for the synthesis of cyclic 3-aryl- and heteroaryl-substituted 1,2-dicarbonyl compounds with different ring sizes by using a Suzuki cross-coupling reaction between 3-halo-1,2-dicarbonyl compounds and arylboronic acids is developed. The 3-halo-1,2-dicarbonyl substrates are easily… read more here.
Keywords: cyclic aryl; synthesis cyclic; substituted dicarbonyl; dicarbonyl compounds ... See more keywords