Cyclic Cystine-Bridged Peptides from the Marine Sponge Clathria basilana Induce Apoptosis in Tumor Cells and Depolarize the Bacterial Cytoplasmic Membrane.
Sign Up to like & getrecommendations! Published in 2017 at "Journal of natural products"
DOI: 10.1021/acs.jnatprod.7b00477
Abstract: Investigation of the sponge Clathria basilana collected in Indonesia afforded five new peptides, including microcionamides C (1) and D (2), gombamides B (4), C (5), and D (6), and an unusual amide, (E)-2-amino-3-methyl-N-styrylbutanamide (7), along… read more here.
Keywords: cyclic cystine; clathria basilana; cystine bridged; sponge clathria ... See more keywords
Cellular Uptake and Cytosolic Delivery of a Cyclic Cystine Knot Scaffold.
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DOI: 10.1021/acschembio.0c00297
Abstract: Cyclotides are macrocyclic peptides that have exceptionally stable structures and been reported to penetrate cells, making them promising scaffolds for the delivery of peptide inhibitory sequences to target intracellular proteins. However, their cellular uptake and… read more here.
Keywords: cytosolic delivery; delivery cyclic; cyclic cystine; delivery ... See more keywords