Diastereodivergent α-Homoallylation of Cyclic Enones.
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DOI: 10.1021/acs.orglett.3c04151
Abstract: α,β-Unsaturated carbonyls are essential structural motifs for nucleophiles of disease-related proteins. Methods for stereoselective functionalizations at the α-position include the Morita-Baylis-Hillman, Negishi, Sonogashira, Stille, and Rauhut-Currier reactions. Described here is a method for the diastereodivergent… read more here.
Keywords: diastereodivergent homoallylation; homoallylation cyclic; cyclic enones; sigmatropic rearrangement ... See more keywords
Electrophilic reactivities of cyclic enones and α,β-unsaturated lactones†
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DOI: 10.1039/d0sc06628a
Abstract: The reactivities of cyclic enones and α,β-unsaturated lactones were characterized by following the kinetics of their reactions with colored carbon-centered reference nucleophiles in DMSO at 20 °C. The experimentally determined second-order rate constants k2 were… read more here.
Keywords: unsaturated lactones; cyclic enones; enones unsaturated; reactivity ... See more keywords