Construction of Fluorinated Amino Acid Derivatives via Cobalt-Catalyzed Oxidative Difunctionalization of Cyclic Ethers.
Sign Up to like & getrecommendations! Published in 2022 at "Organic letters"
DOI: 10.1021/acs.orglett.1c04048
Abstract: Via difunctionalization of the α- and β-sites of cyclic ethers, we herein demonstrate a new synthetic method for the efficient construction of novel fluorinated γ-amino acid esters by employing a CoBr2/m-CPBA catalyst system. Several cyclic… read more here.
Keywords: cyclic ethers; difunctionalization; amino acid; construction ... See more keywords
Visible-Light-Induced C-O Bond Formation for the Construction of Five- and Six-Membered Cyclic Ethers and Lactones.
Sign Up to like & getrecommendations! Published in 2018 at "Organic letters"
DOI: 10.1021/acs.orglett.8b03166
Abstract: Visible-light-induced intramolecular C-O bond formation was developed using 2,4,6-triphenylpyrylium tetrafluoroborate (TPT), which allows the regiocontrolled construction of cyclic ethers and lactones. The reaction is likely to proceed through the single-electron oxidation of the phenyl group,… read more here.
Keywords: bond formation; light induced; cyclic ethers; visible light ... See more keywords
Organocatalytic Coupling of Bromo-Lactide with Cyclic Ethers and Carbonates to Chiral Bromo-Diesters: NHC or Anion Catalysis?
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DOI: 10.1021/acscatal.7b00794
Abstract: In the presence of a N-heterocyclic carbene (NHC) in THF, Br-substituted l-lactide (Br-LA) unexpectedly undergoes exclusive coupling with THF to form a chiral ω-bromo-α-keto-diester. This coupling reaction is completely selective (in a precise 1:1 fashion),… read more here.
Keywords: anion; coupling; bromo; cyclic ethers ... See more keywords
Site- and Enantiodifferentiating C(sp3)-H Oxidation Enables Asymmetric Access to Structurally and Stereochemically Diverse Saturated Cyclic Ethers.
Sign Up to like & getrecommendations! Published in 2020 at "Journal of the American Chemical Society"
DOI: 10.1021/jacs.0c09636
Abstract: A manganese-catalyzed site- and enantiodifferentiating oxidation of C(sp3)-H bonds in saturated cyclic ethers has been described. The mild and practical method is applicable to a range of tetrahydrofurans, tetrahydropyrans, and medium-sized cyclic ethers with multiple… read more here.
Keywords: saturated cyclic; cyclic ethers; site enantiodifferentiating; site ... See more keywords
Cyclic ether synthesis from diols using trimethyl phosphate.
Sign Up to like & getrecommendations! Published in 2017 at "Chemical communications"
DOI: 10.1039/c7cc01514c
Abstract: Cyclic ethers have been effectively synthesized via the intramolecular cyclization of diols using trimethyl phosphate and NaH. The present cyclization could proceed at room temperature to produce 5-7 membered cyclic ethers in good to excellent… read more here.
Keywords: trimethyl phosphate; using trimethyl; cyclic ether; cyclic ethers ... See more keywords
FeCl3-Catalyzed synthesis of pyrrolo[1,2-a]quinoxaline derivatives from 1-(2-aminophenyl)pyrroles through annulation and cleavage of cyclic ethers.
Sign Up to like & getrecommendations! Published in 2017 at "Chemical communications"
DOI: 10.1039/c7cc07089f
Abstract: A straightforward Fe-catalyzed method for the synthesis of pyrrolo[1,2-a]quinoxalines from 1-(2-aminophenyl)pyrroles and cyclic ethers, which includes functionalization of C(sp3)-H bonds and the construction of C-C and C-N bonds, has been developed. The features of this… read more here.
Keywords: aminophenyl pyrroles; synthesis pyrrolo; pyrrolo; cyclic ethers ... See more keywords
Direct functionalization of cyclic ethers with maleimide iodides via free radial-mediated sp3 C-H activation.
Sign Up to like & getrecommendations! Published in 2021 at "Chemical communications"
DOI: 10.1039/d1cc01484f
Abstract: Cyclic ethers are important scaffolds employed in the synthesis of various natural products and pharmaceutical ingredients. A novel free radical-initiated reaction between cyclic ethers and maleimide iodides through C-H activation is developed, avoiding the use… read more here.
Keywords: activation; maleimide iodides; cyclic ethers; ethers maleimide ... See more keywords
Composition of the Solvation Shell of the Selected Cyclic Ethers (1,4-Dioxane, 12-Crown-4, 15-Crown-5 and 18-Crown-6) in a Mixture of Formamide with Water at Four Temperatures
Sign Up to like & getrecommendations! Published in 2023 at "Molecules"
DOI: 10.3390/molecules28052169
Abstract: The solution enthalpy of 15-crown-5 and 18-crown-6 ethers in the mixture of formamide (F) and water (W) was measured at four temperatures: 293.15 K, 298.15 K, 303.15 K, 308.15 K. The standard molar enthalpy of… read more here.
Keywords: cyclic ethers; crown crown; mixture formamide; solvation ... See more keywords