Occurrence of cyclic imines in European commercial seafood and consumers risk assessment
Sign Up to like & getrecommendations! Published in 2018 at "Environmental Research"
DOI: 10.1016/j.envres.2017.11.028
Abstract: ABSTRACT Cyclic imines constitute a quite recently discovered group of marine biotoxins that act on neural receptors and that bioaccumulate in seafood. They are grouped together due to the imino group functioning as their common… read more here.
Keywords: cis; risk assessment; seafood; cyclic imines ... See more keywords
Iridium-Catalyzed Asymmetric Hydrogenation of Sterically Hindered Cyclic Imines for Enantioselective Synthesis of Tetrahydroisoquinolines.
Sign Up to like & getrecommendations! Published in 2020 at "Organic letters"
DOI: 10.1021/acs.orglett.0c03858
Abstract: An efficient enantioselective hydrogenation of sterically hindered cyclic imines catalyzed by the Ir-tBu-ax-Josiphos complex has been described, producing a series of useful chiral bulky tetrahydroisoquinoline analogs in high isolated yields (85-96%) with good to excellent… read more here.
Keywords: hindered cyclic; sterically hindered; iridium catalyzed; cyclic imines ... See more keywords
Difunctionalization of Sulfamate-Derived Cyclic Imines through Phosphine Catalysis.
Sign Up to like & getrecommendations! Published in 2025 at "Organic letters"
DOI: 10.1021/acs.orglett.5c01703
Abstract: With the use of alkynyl 1,2-diones as phosphine acceptors and H2O as a reaction partner, an unprecedented phosphine-catalyzed three-component difunctionalization of sulfamate-derived cyclic imines was achieved, providing a wide range of highly functionalized cyclic sulfonamide… read more here.
Keywords: derived cyclic; sulfamate derived; imines phosphine; difunctionalization sulfamate ... See more keywords
Rh(III)-Catalyzed Diastereodivergent Spiroannulation of Cyclic Imines with Activated Alkenes.
Sign Up to like & getrecommendations! Published in 2017 at "Organic letters"
DOI: 10.1021/acs.orglett.7b02678
Abstract: Rh(III)-catalyzed [3 + 2] annulation of cyclic N-sulfonyl or N-acyl ketimines with activated alkenes has been realized, leading to the synthesis of spirocycles with three continuous stereogenic centers. This atom-economic reaction proceeded efficiently under mild… read more here.
Keywords: spiroannulation cyclic; catalyzed diastereodivergent; diastereodivergent spiroannulation; cyclic imines ... See more keywords
Phosphine-Catalyzed [4 + 2] Annulation of Allenoate with Sulfamate-Derived Cyclic Imines: A Reaction Mode Involving γ'-Carbon of α-Substituted Allenoate.
Sign Up to like & getrecommendations! Published in 2017 at "Organic letters"
DOI: 10.1021/acs.orglett.7b03175
Abstract: A phosphine-catalyzed [4 + 2] cycloaddition of cyclic α-substituted allenoates with sulfamate-derived cyclic imines has been reported. Using dibenzylphenylphosphine as the nucleophilic catalyst, the reaction worked efficiently to yield various fused multicyclic heterocyclic compounds in… read more here.
Keywords: phosphine catalyzed; reaction mode; cyclic imines; reaction ... See more keywords
Cyclic Imines in Ugi and Ugi-Type Reactions.
Sign Up to like & getrecommendations! Published in 2020 at "ACS combinatorial science"
DOI: 10.1021/acscombsci.0c00046
Abstract: Ugi four-component reactions (U-4CRs) are widely recognized as being highly efficient for the synthesis of pseudopeptides. However, the products of these reactions are not so interesting as drug candidates because they are not conformationally restricted… read more here.
Keywords: imines ugi; component; cyclic imines; ugi type ... See more keywords
Annulation Reactions of Isoquinolinium Ylides with Sulfamate-Derived Cyclic Imines toward Polycyclic 1,3-Benzoxazepine Heterocycles
Sign Up to like & getrecommendations! Published in 2024 at "Synthesis"
DOI: 10.1055/a-2349-6944
Abstract: A dearomatization-guided and (3+2) cycloaddition-triggered annulation reaction of in situ formed isoquinolinium ylides with sulfamate-derived cyclic imines is reported, offering a cogent synthesis of tetracyclic 1,3-benzoxazepine frameworks in high yields. The protocol features successive ring-forming… read more here.
Keywords: isoquinolinium ylides; derived cyclic; sulfamate derived; benzoxazepine ... See more keywords
Cyclic Imines and Their Salts as Universal Precursors in the Synthesis of Nitrogen-Containing Alkaloids
Sign Up to like & getrecommendations! Published in 2024 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms26010288
Abstract: Alkaloids are predominantly nitrogen-containing heterocyclic compounds that are usually isolated from plants, and sometimes from insects or animals. Alkaloids are one of the most important types of natural products due to their diverse biological activities… read more here.
Keywords: salts universal; alkaloids cyclic; nitrogen containing; cyclic imines ... See more keywords
Solvent-Free C-3 Coupling of Azaindoles with Cyclic Imines
Sign Up to like & getrecommendations! Published in 2019 at "Molecules"
DOI: 10.3390/molecules24193578
Abstract: By direct coupling 7-azaindole and cyclic imines, such as 3,4-dihydroisoquinoline, 6,7-dihydrothieno[3,2-c]pyridine, 3,4-dihydro-β-carboline, and 4,5-dihydro-3H-benz[c]azepine, new 3-substituted 7-azaindole derivatives have been synthesized. The reaction was extended to 4-azaindoles and 6-azaindoles, as electron-rich aromatic compounds. The lowest… read more here.
Keywords: azaindoles cyclic; free coupling; cyclic imines; coupling azaindoles ... See more keywords