Cp2TiCl2-catalyzed reaction of symmetrical alkynes with α,ω-dicarboxylic acid esters and ЕtAlCl2: An original pathway to С5-С6 cyclic ketones and tetrasubstituted furans
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DOI: 10.1016/j.tet.2018.04.008
Abstract: Abstract An original method for the synthesis of С5-С6 cyclic ketones and tetrasubstituted furans was developed based on the Cp2TiCl2-catalyzed reaction of symmetrical alkynes and α,ω-dicarboxylates in the presence of Mg and ЕtAlCl2. The length… read more here.
Keywords: acid esters; dicarboxylic acid; tetrasubstituted furans; cyclic ketones ... See more keywords
Palladium-catalysed α-allylation of chiral sulfinimines derived from symmetric cyclic ketones
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DOI: 10.1016/j.tetlet.2017.02.008
Abstract: Abstract A diastereoselective mono-allylation reaction at the α-position of symmetric cyclic ketones by using tert-butanesulfinamide as a chiral auxiliary is explored. Excellent yields and high diastereomeric ratios were achieved under palladium(0) catalysis in the presence… read more here.
Keywords: symmetric cyclic; catalysed allylation; allylation chiral; cyclic ketones ... See more keywords
Metal-free oxidative cyclization of 2-aminobenzothiazoles and cyclic ketones enabled by the combination of elemental sulfur and oxygen
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DOI: 10.1039/c7gc02014g
Abstract: Metal-free oxidative cyclization for the one-pot synthesis of benzo[d]imidazo[2,1-b]thiazoles from 2-aminobenzothiazoles and cyclic ketones is described. Elemental sulfur combined with molecular oxygen as the benign co-oxidant was found to be unique and highly effective to… read more here.
Keywords: aminobenzothiazoles cyclic; free oxidative; metal; cyclic ketones ... See more keywords
Straightforward access to densely substituted chiral succinimides through enantioselective organocatalyzed Michael addition of α-alkyl-cyclic ketones to maleimides
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DOI: 10.1039/c9qo01463b
Abstract: A simple organocatalytic system provides efficient access to a series of densely substituted chiral succinimides bearing a quaternary–tertiary carbon stereocenter sequence in good yields, with high diastereo- and enantioselectivities through enantioselective conjugate addition of unreactive… read more here.
Keywords: alkyl cyclic; ketones maleimides; substituted chiral; densely substituted ... See more keywords
Palladium-catalyzed asymmetric hydrogenation of 2-aryl cyclic ketones for the synthesis of trans cycloalkanols through dynamic kinetic resolution under acidic conditions.
Sign Up to like & getrecommendations! Published in 2020 at "Chemical communications"
DOI: 10.1039/d0cc00480d
Abstract: The first efficient palladium-catalyzed asymmetric hydrogenation of 2-aryl cyclic ketones has been described through dynamic kinetic resolution under acidic conditions, providing a facile access to chiral trans cycloalkanol derivatives with excellent enantioselectivities. read more here.
Keywords: catalyzed asymmetric; hydrogenation aryl; aryl cyclic; asymmetric hydrogenation ... See more keywords
Synthesis of functionalized spirocyclic oxetanes through Paternò-Büchi reactions of cyclic ketones and maleic acid derivatives.
Sign Up to like & getrecommendations! Published in 2022 at "Chemical communications"
DOI: 10.1039/d2cc06459f
Abstract: A telescoped three-step sequence to functionalised spirocyclic oxetanes is reported, involving Paternò-Büchi reactions between maleic acid derivatives and cyclic ketones. p-Xylene suppresses the competing alkene dimerization that has plagued previous work, allowing access to 35… read more here.
Keywords: patern chi; spirocyclic oxetanes; chi reactions; cyclic ketones ... See more keywords