Reductive Electrophotocatalytic α‐C−H Arylation of Cyclic Ketones with Aryl Chlorides
Sign Up to like & getrecommendations! Published in 2024 at "ChemCatChem"
DOI: 10.1002/cctc.202400635
Abstract: α‐Aryl cyclocarbonyls are important building blocks in organic synthesis. While many methods have been developed for their synthesis, the use of readily available and inexpensive aryl chlorides as the arylating reagent remains rare. Herein, we… read more here.
Keywords: aryl chlorides; reductive electrophotocatalytic; ketones aryl; cyclic ketones ... See more keywords
Cp2TiCl2-catalyzed reaction of symmetrical alkynes with α,ω-dicarboxylic acid esters and ЕtAlCl2: An original pathway to С5-С6 cyclic ketones and tetrasubstituted furans
Sign Up to like & getrecommendations! Published in 2018 at "Tetrahedron"
DOI: 10.1016/j.tet.2018.04.008
Abstract: Abstract An original method for the synthesis of С5-С6 cyclic ketones and tetrasubstituted furans was developed based on the Cp2TiCl2-catalyzed reaction of symmetrical alkynes and α,ω-dicarboxylates in the presence of Mg and ЕtAlCl2. The length… read more here.
Keywords: acid esters; dicarboxylic acid; tetrasubstituted furans; cyclic ketones ... See more keywords
Palladium-catalysed α-allylation of chiral sulfinimines derived from symmetric cyclic ketones
Sign Up to like & getrecommendations! Published in 2017 at "Tetrahedron Letters"
DOI: 10.1016/j.tetlet.2017.02.008
Abstract: Abstract A diastereoselective mono-allylation reaction at the α-position of symmetric cyclic ketones by using tert-butanesulfinamide as a chiral auxiliary is explored. Excellent yields and high diastereomeric ratios were achieved under palladium(0) catalysis in the presence… read more here.
Keywords: symmetric cyclic; catalysed allylation; allylation chiral; cyclic ketones ... See more keywords
Cu(II) Metal-Organic Framework as a Recyclable Heterogeneous Catalyst for Substituted Pyridine Synthesis from Cyclic Ketones with Propargylamine.
Sign Up to like & getrecommendations! Published in 2025 at "Inorganic chemistry"
DOI: 10.1021/acs.inorgchem.4c04601
Abstract: The creation of efficient and stable metal-organic framework (MOF) catalysts with coordinatively unsaturated metal sites is critical in modern organic synthesis. Herein, we reported one new Cu(II)-MOF with the chemical formula of {[Cu(L)(H2O)]·2DMA·H2O}∞ (1) (H2L… read more here.
Keywords: organic framework; cyclic ketones; metal organic; ketones propargylamine ... See more keywords
Ni(II)-Catalyzed Site- and Regioselective α-Alkenylation of Cyclic Ketones with Alkenes.
Sign Up to like & getrecommendations! Published in 2025 at "Organic letters"
DOI: 10.1021/acs.orglett.5c00745
Abstract: Herein, a nickel-catalyzed α-alkenylation reaction of asymmetric cyclic ketones at the sterically hindered α-position with alkenes is disclosed. The high regioselectivity might originate from the acid-catalyzed enolization reaction, selectively generating the thermodynamically favored enol. The… read more here.
Keywords: alkenylation; regioselective alkenylation; cyclic ketones; site regioselective ... See more keywords
Diastereoselective Synthesis of Cyclic and Spirocyclic Quaternary Carbons via Iron-Catalyzed Ring Contraction of Cyclic Ketones: A Formal Synthesis of Perhydrohistrionicotoxin.
Sign Up to like & getrecommendations! Published in 2025 at "Organic letters"
DOI: 10.1021/acs.orglett.5c02888
Abstract: The iron-catalyzed hydrogen atom transfer (HAT)-initiated Dowd-Beckwith rearrangement presents a new approach for synthesizing cyclic and spirocyclic quaternary carbons from readily available β-keto esters and cyclic diketones with high yields. This reaction proceeds in a… read more here.
Keywords: spirocyclic quaternary; quaternary carbons; cyclic spirocyclic; synthesis ... See more keywords
Metal-free oxidative cyclization of 2-aminobenzothiazoles and cyclic ketones enabled by the combination of elemental sulfur and oxygen
Sign Up to like & getrecommendations! Published in 2017 at "Green Chemistry"
DOI: 10.1039/c7gc02014g
Abstract: Metal-free oxidative cyclization for the one-pot synthesis of benzo[d]imidazo[2,1-b]thiazoles from 2-aminobenzothiazoles and cyclic ketones is described. Elemental sulfur combined with molecular oxygen as the benign co-oxidant was found to be unique and highly effective to… read more here.
Keywords: aminobenzothiazoles cyclic; free oxidative; metal; cyclic ketones ... See more keywords
Straightforward access to densely substituted chiral succinimides through enantioselective organocatalyzed Michael addition of α-alkyl-cyclic ketones to maleimides
Sign Up to like & getrecommendations! Published in 2020 at "Organic chemistry frontiers"
DOI: 10.1039/c9qo01463b
Abstract: A simple organocatalytic system provides efficient access to a series of densely substituted chiral succinimides bearing a quaternary–tertiary carbon stereocenter sequence in good yields, with high diastereo- and enantioselectivities through enantioselective conjugate addition of unreactive… read more here.
Keywords: alkyl cyclic; ketones maleimides; substituted chiral; densely substituted ... See more keywords
Palladium-catalyzed asymmetric hydrogenation of 2-aryl cyclic ketones for the synthesis of trans cycloalkanols through dynamic kinetic resolution under acidic conditions.
Sign Up to like & getrecommendations! Published in 2020 at "Chemical communications"
DOI: 10.1039/d0cc00480d
Abstract: The first efficient palladium-catalyzed asymmetric hydrogenation of 2-aryl cyclic ketones has been described through dynamic kinetic resolution under acidic conditions, providing a facile access to chiral trans cycloalkanol derivatives with excellent enantioselectivities. read more here.
Keywords: catalyzed asymmetric; hydrogenation aryl; aryl cyclic; asymmetric hydrogenation ... See more keywords
Synthesis of functionalized spirocyclic oxetanes through Paternò-Büchi reactions of cyclic ketones and maleic acid derivatives.
Sign Up to like & getrecommendations! Published in 2022 at "Chemical communications"
DOI: 10.1039/d2cc06459f
Abstract: A telescoped three-step sequence to functionalised spirocyclic oxetanes is reported, involving Paternò-Büchi reactions between maleic acid derivatives and cyclic ketones. p-Xylene suppresses the competing alkene dimerization that has plagued previous work, allowing access to 35… read more here.
Keywords: patern chi; spirocyclic oxetanes; chi reactions; cyclic ketones ... See more keywords
Using Cyclic Ketones to Synthesize New 3,5,6,7,8,9-Hexahydro-pyrazolo[1,5-a]quinoline Derivatives with Antiproliferative Activities: Morphological Studies.
Sign Up to like & getrecommendations! Published in 2025 at "Current cancer drug targets"
DOI: 10.2174/0115680096356497250210064209
Abstract: BACKGROUND Quinoline derivatives, often incorporating other heterocyclic structures, have shown a wide range of therapeutic potential, especially in the treatment of cancer. These compounds have demonstrated significant anticancer activity against various cell lines, including HeLa… read more here.
Keywords: cancer; pyrazolo quinoline; cyclic ketones; cell ... See more keywords