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Published in 2023 at "Journal of medicinal chemistry"
DOI: 10.1021/acs.jmedchem.2c01344
Abstract: The current global issue of antibiotic resistance is serious, and there is an urgent requirement of developing novel antibiotics. Octapeptins have recently regained interest because of their activities against resistant Gram-negative bacteria. We synthesized four…
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Keywords:
cyclic lipopeptide;
activity;
synthesis;
renal cytotoxicity ... See more keywords
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Published in 2018 at "Molecular Simulation"
DOI: 10.1080/08927022.2017.1384632
Abstract: Abstract According to experimental studies, Bacillomycin D has strong antimicrobial activities, but the antimicrobial mechanism is still unknown. In this paper, the interaction mechanisms between this cyclic lipopeptide and three different charged cell membranes are…
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Keywords:
lipopeptide bacillomycin;
cyclic lipopeptide;
coarse grained;
cell membranes ... See more keywords
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Published in 2018 at "Scandinavian Journal of Immunology"
DOI: 10.1111/sji.12698
Abstract: Cyclic lipopeptides such as surfactin and polymyxin have potent mucosal adjuvant properties. Cyclic lipopeptides are tensioactive compounds, but the relationship between adjuvanticity and surface activity is unknown. Here, we show that the critical micelle concentration…
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Keywords:
critical micelle;
size;
cyclic lipopeptides;
concentration ... See more keywords
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2
Published in 2022 at "Frontiers in Molecular Biosciences"
DOI: 10.3389/fmolb.2022.1064742
Abstract: Tolaasin II is an amphiphilic, membrane-active, cyclic lipopeptide produced by Pseudomonas tolaasii and is responsible for brown blotch disease in mushroom. To better understand the mode of action and membrane selectivity of tolaasin II and…
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Keywords:
cyclic lipopeptide;
tolaasin;
activity;
membrane ... See more keywords