Cyclic nucleotides in archaea: Cyclic di‐AMP in the archaeon Haloferax volcanii and its putative role
Sign Up to like & getrecommendations! Published in 2019 at "MicrobiologyOpen"
DOI: 10.1002/mbo3.829
Abstract: The role of cyclic nucleotides as second messengers for intracellular signal transduction has been well described in bacteria. One recently discovered bacterial second messenger is cyclic di‐adenylate monophosphate (c‐di‐AMP), which has been demonstrated to be… read more here.
Keywords: amp archaeon; amp; haloferax volcanii; cyclic nucleotides ... See more keywords
Interaction of Epac with Non-canonical Cyclic Nucleotides.
Sign Up to like & getrecommendations! Published in 2017 at "Handbook of experimental pharmacology"
DOI: 10.1007/164_2015_37
Abstract: Epac1 and Epac2 are cyclic nucleotide-binding (CNB) domain containing proteins, which were originally identified as cAMP-regulated guanine nucleotide exchange factors (GEFs) for the small G-protein Rap. Therefore, Epac proteins founded next to protein kinase A… read more here.
Keywords: epac non; interaction epac; non canonical; cyclic nucleotides ... See more keywords
Mass Spectrometric Analysis of Non-canonical Cyclic Nucleotides.
Sign Up to like & getrecommendations! Published in 2017 at "Handbook of experimental pharmacology"
DOI: 10.1007/164_2016_5001
Abstract: Contemporary investigations regarding the (patho)physiological roles of the non-canonical cyclic nucleoside monophosphates (cNMP) cytidine 3',5'-cyclic monophosphate (cCMP) and uridine 3',5'-cyclic monophosphate (cUMP) have been hampered by the lack of highly specific and sensitive analytic methods… read more here.
Keywords: mass spectrometric; canonical cyclic; non canonical; cyclic nucleotides ... See more keywords
Role of Cyclic Nucleotides in the Effect of Hydrogen Sulfide on Contractions of Rat Jejunum
Sign Up to like & getrecommendations! Published in 2017 at "Bulletin of Experimental Biology and Medicine"
DOI: 10.1007/s10517-017-3726-x
Abstract: We studied the role of cyclic nucleotides in the influence of hydrogen sulfide (H2S) donor, sodium hydrosulfide (NaHS, 200 μM), on motor activity of rat jejunum. NaHS reduced spontaneous and carbachol-induced contractions of rat jejunum… read more here.
Keywords: hydrogen sulfide; contractions rat; rat jejunum; cyclic nucleotides ... See more keywords
Cyclic nucleotides and myometrial contractility
Sign Up to like & getrecommendations! Published in 2020 at "Current Opinion in Physiology"
DOI: 10.1016/j.cophys.2019.10.014
Abstract: Cyclic nucleotides determine a spatiotemporally regulated system that modulates uterine myometrial contractility and parturition timing. Adenylate and guanylate cyclases synthesize cAMP and cGMP upon β-adrenergic, natriuretic peptide, and nitric oxide stimulation. Before parturition, cAMP suppresses… read more here.
Keywords: camp; nucleotides myometrial; cyclic nucleotides; parturition ... See more keywords
Regulation of sinoatrial funny channels by cyclic nucleotides: From adrenaline and IK2 to direct binding of ligands to protein subunits.
Sign Up to like & getrecommendations! Published in 2021 at "Progress in biophysics and molecular biology"
DOI: 10.1016/j.pbiomolbio.2021.06.010
Abstract: The funny current, and the HCN channels that form it, are affected by the direct binding of cyclic nucleotides. Binding of these second messengers causes a depolarizing shift of the activation curve, which leads to… read more here.
Keywords: direct binding; regulation sinoatrial; sinoatrial funny; cyclic nucleotides ... See more keywords