Type III CRISPR–Cas systems produce cyclic oligoadenylate second messengers
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DOI: 10.1038/nature23467
Abstract: In many prokaryotes, type III clustered regularly interspaced short palindromic repeat (CRISPR)–CRISPR-associated (Cas) systems detect and degrade invasive genetic elements by an RNA-guided, RNA-targeting multisubunit interference complex. The CRISPR-associated protein Csm6 additionally contributes to interference… read more here.
Keywords: cyclic oligoadenylate; crispr; interference; cas systems ... See more keywords