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First total synthesis of cyclic pentadepsipeptides Hikiamides A–C

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0 Published in 2018 at "Tetrahedron Letters"

DOI: 10.1016/j.tetlet.2018.01.096

Abstract: Abstract The first total syntheses of naturally occurring cyclodepsipeptides Hikiamides A–C are described. The key linear pentapeptide precursors, prepared efficiently via Fmoc-solid-phase synthesis, were cyclized in dilute solution to provide the target Hikiamides A–C. The… read more here.

Keywords: synthesis cyclic; pentadepsipeptides hikiamides; first total; total synthesis ... See more keywords