A 19F-Labeled Isothiocyanate Derivatizing Agent for the Chiral Discrimination of Cyclic Secondary Amines.
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DOI: 10.1021/acs.analchem.5c04345
Abstract: Due to the widespread applications of cyclic secondary amines in drug development, rapid methods for detecting and distinguishing chiral cyclic secondary amines have become increasingly important. In this study, we successfully present a derivatizing strategy… read more here.
Keywords: analysis; secondary amines; labeled isothiocyanate; cyclic secondary ... See more keywords
Iron-Catalyzed Aerobic Dehydrogenative Kinetic Resolution of Cyclic Secondary Amines.
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DOI: 10.1021/jacs.9b00615
Abstract: A nonenzymatic iron-catalyzed dehydrogenative kinetic resolution of cyclic secondary amines using air as an oxidant has been reported. The economical and practical method is applicable to a series of cyclic benzylic amines, including 5,6-dihydrophenanthridines and… read more here.
Keywords: cyclic secondary; resolution cyclic; dehydrogenative kinetic; kinetic resolution ... See more keywords
Expedient Ni(OTf)2/visible light photoredox-catalyzed annulation of donor-acceptor cyclopropanes with cyclic secondary amines.
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DOI: 10.1039/d2cc02941c
Abstract: The annulative coupling of donor-acceptor cyclopropanes with cyclic secondary amines is reported using the combination of Ni(OTf)2 and visible light assisted eosin Y catalysis for tandem C-N and C-C bond formation. The reaction sequence provides… read more here.
Keywords: acceptor cyclopropanes; secondary amines; donor acceptor; cyclopropanes cyclic ... See more keywords