Cyclic stretch regulates immune responses via tank‐binding kinase 1 expression in macrophages
Sign Up to like & getrecommendations! Published in 2022 at "FEBS Open Bio"
DOI: 10.1002/2211-5463.13526
Abstract: Macrophages distributed in tissues throughout the body contribute to homeostasis. In the inflammatory state, macrophages undergo mechanical stress that regulates the signal transduction of immune responses and various cellular functions. However, the effects of the… read more here.
Keywords: stretch; immune responses; cyclic stretch; tank binding ... See more keywords
Numerical predictions of shear stress and cyclic stretch in pulmonary hypertension due to left heart failure
Sign Up to like & getrecommendations! Published in 2022 at "Biomechanics and Modeling in Mechanobiology"
DOI: 10.1007/s10237-021-01538-1
Abstract: Isolated post-capillary pulmonary hypertension (Ipc-PH) occurs due to left heart failure, which contributes to 1 out of every 9 deaths in the United States. In some patients, through unknown mechanisms, Ipc-PH transitions to combined pre-/post-capillary… read more here.
Keywords: cyclic stretch; due left; shear stress; left heart ... See more keywords
Orthogonal alignment of multilayered MC3T3-E1 cells induced by cyclic stretch
Sign Up to like & getrecommendations! Published in 2025 at "Biomechanics and Modeling in Mechanobiology"
DOI: 10.1007/s10237-025-01978-z
Abstract: When cyclic stretch is applied to a monolayer of cells cultured on an elastic substrate, many types of cells align in the direction perpendicular to the stretch or along the direction of minimal substrate strain.… read more here.
Keywords: layer cells; direction stretch; stretch; cyclic stretch ... See more keywords
Combined effects of cyclic stretch and TNF-α on the osteogenic differentiation in MC3T3-E1 cells.
Sign Up to like & getrecommendations! Published in 2021 at "Archives of oral biology"
DOI: 10.1016/j.archoralbio.2021.105222
Abstract: OBJECTIVE The study aimed to investigate the combined effects of cyclic stretch and tumor necrosis factor-alpha (TNF-α) on the osteogenic differentiation of MC3T3-E1 cells and the role of the nuclear factor-kappaB (NF-κB) signaling pathway in… read more here.
Keywords: tnf; cyclic stretch; osteogenic differentiation; mc3t3 cells ... See more keywords
Cyclic stretch promotes vascular homing of endothelial progenitor cells via Acsl1 regulation of mitochondrial fatty acid oxidation.
Sign Up to like & getrecommendations! Published in 2023 at "Proceedings of the National Academy of Sciences of the United States of America"
DOI: 10.1073/pnas.2219630120
Abstract: Endothelial progenitor cells (EPCs) play an important role in vascular repair and re-endothelialization after vessel injury. EPCs in blood vessels are subjected to cyclic stretch (CS) due to the pulsatile pressure, but the role of… read more here.
Keywords: endothelial progenitor; acid oxidation; cyclic stretch; progenitor cells ... See more keywords
Active matter under cyclic stretch: Modeling microtubule alignment and bundling.
Sign Up to like & getrecommendations! Published in 2025 at "Physical review. E"
DOI: 10.1103/qysz-9fk3
Abstract: We investigate the behavior of self-propelled particles under cyclic stretching, inspired by the characteristic pattern dynamics observed in microtubule (MT) motility assays subjected to uniaxial cyclic substrate stretching. We develop a self-propelled particle model that… read more here.
Keywords: matter cyclic; stretch modeling; cyclic stretch; modeling microtubule ... See more keywords
High-magnitude cyclic stretch induces protein sialylation and RNA de-sialylation at the alveolar epithelial membrane
Sign Up to like & getrecommendations! Published in 2024 at "Physiology"
DOI: 10.1152/physiol.2024.39.s1.1761
Abstract: Sialylated glycans such as sialoglycoproteins, sialoglycolipids and sialoglycoRNA are ubiquitous in the glycocalyx of cells where they play a key role in barrier function, mechanosensation, infection, immune cell traffcking, and inflammation. These functions are particularly… read more here.
Keywords: cyclic stretch; physiology; high magnitude; alveolar epithelial ... See more keywords
Naringin Inhibits Apoptosis Induced by Cyclic Stretch in Rat Annular Cells and Partially Attenuates Disc Degeneration by Inhibiting the ROS/NF-κB Pathway
Sign Up to like & getrecommendations! Published in 2022 at "Oxidative Medicine and Cellular Longevity"
DOI: 10.1155/2022/6179444
Abstract: Oxidative stress and apoptosis play important roles in the pathogenesis of various degenerative diseases. Previous studies have shown that naringin can exert therapeutic effects in multiple degenerative diseases by resisting oxidative stress and inhibiting apoptosis.… read more here.
Keywords: cyclic stretch; oxidative stress; apoptosis; degeneration ... See more keywords
Mechanical cyclic stretch of the respiration and in vitro microvascular remodeling
Sign Up to like & getrecommendations! Published in 2018 at "European Respiratory Journal"
DOI: 10.1183/13993003.congress-2018.pa4229
Abstract: Abstract Introduction: In addition to mechanical forces caused by blood flow, lung vascular networks undergo additional forces in the form of cyclic stretch from respiration. These forces act on the microvascular wall and play an… read more here.
Keywords: microvasculature; stretch; mechanical cyclic; cyclic stretch ... See more keywords
Cyclic stretch induced oxidative stress by mitochondrial and NADPH oxidase in retinal pigment epithelial cells
Sign Up to like & getrecommendations! Published in 2019 at "BMC Ophthalmology"
DOI: 10.1186/s12886-019-1087-0
Abstract: BackgroundVitreomacular adhesion (VMA) has been reported to associated with age-related macular degeneration (AMD). Understanding the mechanisms underlying cyclic stretch induced in retinal pigment epithelial cells (RPE) may be important for the treatment of VMA-related AMD.MethodCyclic… read more here.
Keywords: epithelial cells; stretch; pigment epithelial; stretch induced ... See more keywords
NAD+/Nrf2 signaling promotes osteogenesis by regulating oxidative level of BMSCs under mechanical stress
Sign Up to like & getrecommendations! Published in 2025 at "Progress in Orthodontics"
DOI: 10.1186/s40510-025-00566-2
Abstract: Mechanical stress triggers an increase in cellular reactive oxygen species (ROS), which is associated with the impairment of osteogenesis. During orthodontic treatment, bone marrow mesenchymal stem cells (BMSCs) experience mechanical stress, yet the oxidative profile… read more here.
Keywords: cyclic stretch; stress; nrf2 signaling; mechanical stress ... See more keywords