Resveratrol prevented experimental pulmonary vascular remodeling via miR-638 regulating NR4A3/cyclin D1 pathway.
Sign Up to like & getrecommendations! Published in 2020 at "Microvascular research"
DOI: 10.1016/j.mvr.2020.103988
Abstract: OBJECTIVE Resveratrol has shown benefit for pulmonary hypertension improvement. Our previous reports showed NR4A3/cyclin D1 pathway promoted pulmonary arterial smooth muscle cells (PASMCs) proliferation. This study tried to explore the mechanism underlying this process, focusing… read more here.
Keywords: resveratrol; mir 638; pulmonary vascular; vascular remodeling ... See more keywords
Targeting the AKT/cyclin D1 pathway to overcome intrinsic and acquired radioresistance of tumors for effective radiotherapy
Sign Up to like & getrecommendations! Published in 2017 at "International Journal of Radiation Biology"
DOI: 10.1080/09553002.2016.1257832
Abstract: Abstract Purpose: Radiotherapy (RT) is a powerful tool in the treatment of cancer, having the advantage of preserving normal tissues. Clinical outcomes of RT are significantly improved by technological advances, enabling increased radiation doses directed… read more here.
Keywords: acquired radioresistance; tumor radioresistance; akt cyclin; radioresistance ... See more keywords