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Published in 2017 at "Tetrahedron"
DOI: 10.1016/j.tet.2016.12.065
Abstract: The cyclisation of N-allyl- and N-homoallylguanidines using DMDO leading to the formation of novel 5- and 6-membered guanidine heterocycles is reported. Several of the products formed displayed weak inhibition of glycosidase enzymes.
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Keywords:
ring opening;
epoxide ring;
opening cyclisation;
intramolecular epoxide ... See more keywords