Pyrrolidines and piperidines bearing chiral tertiary alcohols by nickel-catalyzed enantioselective reductive cyclization of N-alkynones
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DOI: 10.1038/s42004-018-0092-1
Abstract: Pyrrolidines and piperidines are important building blocks in organic synthesis. Numerous methods exist for constructing substituted pyrrolidines and piperidines. However, efficient syntheses of pyrrolidines and piperidines bearing chiral tertiary alcohols are limited. Here we report… read more here.
Keywords: pyrrolidines piperidines; tertiary alcohols; cyclization; chiral tertiary ... See more keywords