Sequential Oxidative and Reductive Radical Cyclization Approach toward Asperparaline C and Synthesis of Its 8-Oxo Analogue.
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DOI: 10.1021/acs.orglett.7b00187
Abstract: The most advanced approach, so far, to the asperparalines is developed. Consecutive oxidative and reductive radical cyclizations serve as the key steps to stereoselectively access the complex fully elaborated skeleton containing the cyclopentane and spiro-succinimide… read more here.
Keywords: sequential oxidative; cyclization approach; radical cyclization; reductive radical ... See more keywords
Intramolecular radical cyclization approach to access highly substituted indolines and 2,3-dihydrobenzofurans under visible-light
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DOI: 10.1039/c8ra01787e
Abstract: The combination of visible-light and tris(trimethylsilyl)silane promoting intramolecular reductive cyclization protocol for the synthesis of functionalized indolines and 2,3-dihydrobenzofurans has been developed. The transformations occur in the absence of transition metal and additional photocatalyst. In… read more here.
Keywords: indolines dihydrobenzofurans; cyclization approach; radical cyclization; visible light ... See more keywords