Ammonium Ylide Mediated Cyclization Reactions
Sign Up to like & getrecommendations! Published in 2018 at "Asian journal of organic chemistry"
DOI: 10.1002/ajoc.201800091
Abstract: The use of readily accessible ammonium ylides for (asymmetric) transformations, especially cyclization reactions, has received considerable attention over the past two decades. A variety of highly enantioselective protocols to facilitate annulation reactions have recently been… read more here.
Keywords: ammonium ylide; cyclization reactions; ylide mediated; mediated cyclization ... See more keywords
Harnessing cascade Suzuki‐cyclization reactions of pyrazolo[3,4‐b]pyridine for the synthesis of tetracyclic fused heteroaromatics
Sign Up to like & getrecommendations! Published in 2017 at "European Journal of Organic Chemistry"
DOI: 10.1002/ejoc.201601242
Abstract: Numerous procedures have been described for the functionalization of pyrazolo[3,4-b]pyridine, mainly nucleophilic substitutions on C-4 position and esterifications/amidations on C-5 position. Thus, we report herein a robust, easy to implement protocol for the Suzuki cross-coupling… read more here.
Keywords: suzuki cyclization; pyrazolo pyridine; harnessing cascade; suzuki ... See more keywords
Sequential Silver‐Catalyzed Oxidative Cyclization Reactions of Unprotected 2‐Alkynylanilines to Anthranils
Sign Up to like & getrecommendations! Published in 2017 at "European Journal of Organic Chemistry"
DOI: 10.1002/ejoc.201601600
Abstract: The full details of the original Ag-catalyzed domino oxidative cyclization reactions of unprotected 2-alkynylanilines with Oxone are described. The influences of several parameters including the substrate features, oxidant, reaction conditions, and catalyst on the reaction… read more here.
Keywords: silver catalyzed; reactions unprotected; cyclization reactions; unprotected alkynylanilines ... See more keywords
Two Complementary Cyclization Reactions for the Chemoselective Synthesis of Spirooxindoles
Sign Up to like & getrecommendations! Published in 2017 at "European Journal of Organic Chemistry"
DOI: 10.1002/ejoc.201701413
Abstract: Two complementary cascade cyclization reactions were described, namely KHSO4-promoted [1+2+3] cyclization and TMSCl-promoted four-molecular cascade cyclization for the concise synthesis of highly functionalized spirooxindoles in excellent yields. Between them, the improved TMSCl-promoted cyclization reaction of… read more here.
Keywords: promoted cyclization; two complementary; cyclization; cyclization reactions ... See more keywords
Organocatalytic Asymmetric Cyclization Reactions with γ‐Hydroxyenones
Sign Up to like & getrecommendations! Published in 2025 at "European Journal of Organic Chemistry"
DOI: 10.1002/ejoc.202500482
Abstract: This review article provides an overview of the recent developments in organocatalytic asymmetric cyclization strategies utilizing γ‐hydroxyenones. Due to the bifunctional nature of γ‐hydroxyenones, it is a powerful building block for synthesizing oxygen‐ and nitrogen‐containing… read more here.
Keywords: chemistry; cyclization; reactions hydroxyenones; asymmetric cyclization ... See more keywords
Divergent Conversion of Double Isocyanides with Alkenyl Bromide to Polysubstituted Pyrroles and 4-Imino-4,5-dihydropyrrolo[3,4-b]pyrrol-6(1H)-one Derivatives by Pd-Catalyzed Tandem Cyclization Reactions.
Sign Up to like & getrecommendations! Published in 2022 at "Organic letters"
DOI: 10.1021/acs.orglett.1c04146
Abstract: Herein a novel and concise approach to pyrrole skeletons via Pd-catalyzed tandem cyclization reactions is investigated. The substrates for the transformation could be readily prepared by phosphoric acid-catalyzed Ugi reactions with available starting materials. In… read more here.
Keywords: catalyzed tandem; cyclization reactions; divergent conversion; tandem cyclization ... See more keywords
Bioorthogonal Cyclization Reactions for the Synthesis of Cytotoxic Drugs in Cancer Treatment
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DOI: 10.1021/acsomega.5c07644
Abstract: Cyclization reactions play a central role in the synthesis of heterocycles, many of which display potent cytotoxicity and are actively being developed as anticancer agents. Recent breakthroughs have enabled these transformations to occur in situ… read more here.
Keywords: cancer; synthesis cytotoxic; reactions synthesis; cyclization ... See more keywords
Divergent Rhodium-Catalyzed Cyclization Reactions of Enoldiazoacetamides with Nitrosoarenes.
Sign Up to like & getrecommendations! Published in 2017 at "Journal of the American Chemical Society"
DOI: 10.1021/jacs.7b05840
Abstract: The first cyclization reactions of enoldiazo compounds with nitrosoarenes have been developed. Under the catalysis of rhodium(II) octanoate, [3 + 2]-cyclization between enoldiazoacetamides and nitrosoarenes occurred through cleavages of the enol double bond and the… read more here.
Keywords: rhodium; rhodium catalyzed; cyclization; enoldiazoacetamides nitrosoarenes ... See more keywords
Cationic cyclization reactions with alkyne terminating groups: a useful tool in biomimetic synthesis.
Sign Up to like & getrecommendations! Published in 2022 at "Chemical communications"
DOI: 10.1039/d1cc05826f
Abstract: Cyclization reactions through cationic intermediates have become a highly valuable tool in organic synthesis. The use of alkynes as the terminating group in this type of cationic process offers wide synthetic possibilities because this group… read more here.
Keywords: cyclization reactions; cationic cyclization; cyclization; biomimetic synthesis ... See more keywords
Recent advances in cyclization reactions of isatins or thioisatins via C-N or C-S bond cleavage
Sign Up to like & getrecommendations! Published in 2021 at "Organic Chemistry Frontiers"
DOI: 10.1039/d1qo00868d
Abstract: The exploration of new reactivity modes and synthetic methods has always been an attractive goal of organic and medicinal chemistry. As potential raw materials for the efficient construction of nitrogen-... read more here.
Keywords: reactions isatins; chemistry; isatins thioisatins; cyclization reactions ... See more keywords
Recent advances in cyclization reactions of pyridinium 1, n-zwitterions (n = 4 and 5): scope and mechanism
Sign Up to like & getrecommendations! Published in 2023 at "Organic Chemistry Frontiers"
DOI: 10.1039/d3qo00228d
Abstract: Nitrogen- and sulfur-containing heterocyclic compounds widely existed in bioactive natural products and drug molecules with unique bioactivity. The synthesis of nitrogen-and sulfur-containing hybrids had always been a hot topic in... read more here.
Keywords: advances cyclization; cyclization reactions; reactions pyridinium; zwitterions scope ... See more keywords