Self-Catalyzed Phototandem Perfluoroalkylation/Cyclization of Unactivated Alkenes: Synthesis of Perfluoroalkyl-Substituted Quinazolinones.
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DOI: 10.1021/acs.orglett.0c04225
Abstract: A novel visible-light-induced radical tandem trifluoromethylation/cyclization of unactivated alkenes with sodium perfluoroalkanesulfinates (Rf = CF3, C3F7, C4F9, C6F13, C8F17) under air atmosphere has been developed. A range of quinazolinones containing unactivated alkene moiety and sodium… read more here.
Keywords: unactivated alkenes; cyclization unactivated; self catalyzed; perfluoroalkyl substituted ... See more keywords