Copper-catalyzed tandem cyclization and vinylation for the synthesis of 2-trifluoromethyl benzofurans
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DOI: 10.1016/j.jfluchem.2019.109418
Abstract: Abstract A copper-catalyzed tandem cyclization and vinylation of 2-chloro-1-(2-bromoaryl)-3,3,3-trifluoropropenes with KOH has been developed for the synthesis of 2-trifluoromethyl benzofuran derivatives. The reaction involves dual C O bonds formation and hydroarylation of aryl trifluoropropynes. This… read more here.
Keywords: tandem cyclization; cyclization vinylation; catalyzed tandem; synthesis trifluoromethyl ... See more keywords