Potential anticancer effects of cyclo(-Pro-Tyr) against N-diethyl nitrosamine induced hepatocellular carcinoma in mouse through PI3K/AKT signaling.
Sign Up to like & getrecommendations! Published in 2021 at "Environmental toxicology"
DOI: 10.1002/tox.23395
Abstract: The oceans are considered as magnificent source of bioactive metabolites, of which marine sponges associated organisms are being the most effective producers of various bioactive molecules. We previously reported that cyclo(-Pro-Tyr) (CPT), a dipeptide from… read more here.
Keywords: hepatocellular carcinoma; pi3k; akt signaling; pro tyr ... See more keywords
2,5-Diketopiperazines from Aspergillus sp., the Endophytic Fungus of Astragalus membranaceus and their Anticancer Assay
Sign Up to like & getrecommendations! Published in 2020 at "Chemistry of Natural Compounds"
DOI: 10.1007/s10600-020-03100-4
Abstract: 2,5-Diketopiperazines are cyclodipeptides obtained by the condensation of two α-amino acids. They not only abound in nature but are often produced as degradation products of polypeptides, especially in processed food and beverages [1]. The 2,5-diketopiperazines… read more here.
Keywords: endophytic fungus; fungus; column; ethyl acetate ... See more keywords
Purification and antifungal characterization of Cyclo (D-Pro-L- Val) from Bacillus amyloliquefaciens Y1 against Fusarium graminearum to control head blight in wheat
Sign Up to like & getrecommendations! Published in 2017 at "Biocatalysis and agricultural biotechnology"
DOI: 10.1016/j.bcab.2017.01.003
Abstract: Abstract This study describes the purification, identification and antifungal characterization of Cyclo ( D -PRO- L - VAL) isolated for the first time from Bacillus amyloliquefaciens Y1 (Y1) against Fusarium graminearum. In primary screening, Y1… read more here.
Keywords: growth graminearum; wheat; cyclo pro; pro val ... See more keywords
Bacterial Lipodepsipeptides and Some of Their Derivatives and Cyclic Dipeptides as Potential Agents for Biocontrol of Pathogenic Bacteria and Fungi of Agrarian Plants
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Agricultural and Food Chemistry"
DOI: 10.1021/acs.jafc.1c08139
Abstract: Biotic stresses (fungi, bacteria, insects, weeds, etc.) are some of the most important causes of the decrease in the quality and quantity of crops that could become an emergency due to a noteworthy increase in… read more here.
Keywords: agrarian plants; pathogenic bacteria; bacterial lipodepsipeptides; bacteria fungi ... See more keywords
Bioactive Phytochemicals from Mulberry: Potential Anti-Inflammatory Effects in Lipopolysaccharide-Stimulated RAW 264.7 Macrophages
Sign Up to like & getrecommendations! Published in 2021 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms22158120
Abstract: The fruits of the mulberry tree (Morus alba L.), known as white mulberry, have been consumed in various forms, including tea, beverages, and desserts, worldwide. As part of an ongoing study to discover bioactive compounds… read more here.
Keywords: anti inflammatory; raw 264; 264 macrophages; stimulated raw ... See more keywords
Structural and Biofunctional Insights into the Cyclo(Pro-Pro-Phe-Phe-) Scaffold from Experimental and In Silico Studies: Melanoma and Beyond
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms23137173
Abstract: Short peptides have great potential as safe and effective anticancer drug leads. Herein, the influence of short cyclic peptides containing the Pro-Pro-Phe-Phe sequence on patient-derived melanoma cells was investigated. Cyclic peptides such as cyclo(Leu-Ile-Ile-Leu-Val-Pro-Pro-Phe-Phe-), called… read more here.
Keywords: phe; melanoma cells; cyclo pro; phe phe ... See more keywords
Comparative Metabolomics Reveals Fungal Conversion of Co-Existing Bacterial Metabolites within a Synthetic Aspergillus-Streptomyces Community
Sign Up to like & getrecommendations! Published in 2021 at "Marine Drugs"
DOI: 10.3390/md19090526
Abstract: In nature, secondary metabolites have been proven to be the essential communication media between co-occurring microorganisms and to influence their relationship with each other. In this study, we conducted a metabolomics survey of the secondary… read more here.
Keywords: communication; community; chemical communication; comparative metabolomics ... See more keywords