An Extended Approach for the Development of Fluorogenic trans‐Cyclooctene–Tetrazine Cycloadditions
Sign Up to like & getrecommendations! Published in 2019 at "Chembiochem"
DOI: 10.1002/cbic.201800711
Abstract: Inverse‐electron‐demand Diels–Alder (iEDDA) cycloaddition between 1,2,4,5‐tetrazines and strained dienophiles belongs among the most popular bioconjugation reactions. In addition to its fast kinetics, this cycloaddition can be tailored to produce fluorescent products from non‐fluorescent starting materials.… read more here.
Keywords: cycloaddition; extended approach; iedda cycloaddition; trans cyclooctene ... See more keywords
Catalytic Asymmetric Huisgen Alkyne–Azide Cycloaddition of Bisalkynes by Copper(I) Nanoparticles
Sign Up to like & getrecommendations! Published in 2018 at "ChemCatChem"
DOI: 10.1002/cctc.201701336
Abstract: The use of chiral ligands to tune the reactivity and enantioselectivity of transition‐metal catalyst for asymmetric transformations is a central challenge in synthetic organic chemistry. In this manuscript, chiral P‐ligand (Tao‐Phos)‐assisted Cu2O‐nanoparticles‐catalyzed asymmetric azide–alkyne Huisgen… read more here.
Keywords: cycloaddition; huisgen; huisgen alkyne; copper ... See more keywords
Ring‐Expanded N‐Heterocyclic Carbenes for Copper‐Mediated Azide–Alkyne Click Cycloaddition Reactions
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DOI: 10.1002/cctc.201701992
Abstract: A series of well‐defined copper(I) complexes bearing ring‐expanded N‐heterocyclic carbene (NHC) ligands has been applied to the azide–alkyne cycloaddition reaction. The obtained results notably showed that the six‐membered NHC ligands outperform well‐established five‐membered ones. [CuI(Mes‐6)]… read more here.
Keywords: heterocyclic carbenes; cycloaddition; copper; azide alkyne ... See more keywords
Reductive Cycloisomerization of Diynes by Supported Palladium Catalysts and Subsequent [4+2] Cycloaddition for One‐Pot Synthesis of Cyclohexenes
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DOI: 10.1002/cctc.201901423
Abstract: Abstract: Supported Pd nanoparticles catalyzed the reductive cycloisomerization of diynes to give 1,3‐dienes, and subsequent intermolecular [4+2] cycloaddition with dienophiles led to cyclohexene derivatives. Various diynes and dienophiles participated in the one‐pot reaction to give… read more here.
Keywords: cycloisomerization diynes; reductive cycloisomerization; cycloaddition; one pot ... See more keywords
The Kinetic Solvent Effect on 1,3-Dipolar Cycloaddition of 2,2,5,5-Tetramethyl-3-imidazoline-3-oxide-1-oxyl.
Sign Up to like & getrecommendations! Published in 2022 at "ChemPlusChem"
DOI: 10.1002/cplu.202200119
Abstract: The use of 2,2,5,5-tetramethyl-3-imidazoline-3-oxide-1-oxyl (1) as a controlling agent in Nitroxide Mediated Polymerization allows for activation of alkoxyamine homolysis by 1,3-dipolar cycloaddition of a vinyl monomer [Edeleva et al. Chem. Commun. 2019, 55, 190-193]. Polymerization can… read more here.
Keywords: dipolar cycloaddition; imidazoline oxide; oxide oxyl; tetramethyl imidazoline ... See more keywords
Schreiner's Thiourea Promoted [2+2] Cycloaddition of Captodative Azetidinones and Nitroolefins
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DOI: 10.1002/ejoc.201601524
Abstract: Strained, captodative benzylidene-azetidinones are demonstrated to function as potent reaction partners in thermal [2+2] cycloaddition with nitro alkenes. The relief of strain during the cycloaddition could be leveraged to secure the kinetic and thermodynamic stability… read more here.
Keywords: cycloaddition; schreiner thiourea; thiourea promoted; captodative azetidinones ... See more keywords
Model Studies for the Preparation of Oxepanes and Fused Compounds by Tandem [4+3] Cycloaddition/Ring‐Opening Metathesis/Cross Metathesis
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DOI: 10.1002/ejoc.201700994
Abstract: Functionalised medium-sized ether rings were prepared in an efficient manner by [4+3] cycloaddition followed by ring-opening metathesis. This procedure provided medium-sized rings, which were shown to be useful for the assembly of fused bicyclic structures… read more here.
Keywords: ring opening; cycloaddition; chemistry; opening metathesis ... See more keywords
Simultaneous Generation and Subsequent Cycloaddition of ortho‐Quinonemethides and Cyclic Enecarbamates Promoted by a Gold/Lewis Acid Catalytic System
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DOI: 10.1002/ejoc.201800679
Abstract: A new catalytic reaction to synthesize structurally complex hexahydrochromeno[2,3-b]pyrrole derivatives from simple 3butynamine and 2-(hydroxymethyl)phenol derivatives is described. The process is promoted by a dual catalytic system formed by a gold complex and a Lewis… read more here.
Keywords: simultaneous generation; lewis acid; cycloaddition; catalytic system ... See more keywords
Dipolar 1,3‐cycloaddition of thioformaldehyde S‐methylide (CH2SCH2) to ethylene and acetylene. A comparison with (valence) isoelectronic O3, SO2, CH2OO and CH2SO
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Computational Chemistry"
DOI: 10.1002/jcc.26946
Abstract: Methods rooted in the density functional theory and in the coupled cluster ansatz were employed to investigate the cycloaddition reactions to ethylene and acetylene of 1,3‐dipolar species including ozone and the derivatives issued from replacement… read more here.
Keywords: so2; methylide ch2sch2; valence isoelectronic; thioformaldehyde methylide ... See more keywords
Regioselective Synthesis of Mono‐ and Dispiropyrazoline Derivatives via 1,3‐dipolar Cycloaddition with Nitrilimines
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DOI: 10.1002/jhet.2684
Abstract: The 1,3-dipolar cycloaddition reaction of (E,E)-1,3-bis(arylidene)indan-2-one with diarylnitrilimines, generated in situ via dehydrohalogenation of the corresponding hydrazonoyl chlorides , affords predominantly monospiropyrazolines and as a mixture of diastereoisomers. Also dispiropyrazolines are formed in moderate yields.… read more here.
Keywords: cycloaddition; mono dispiropyrazoline; synthesis mono; dispiropyrazoline derivatives ... See more keywords
Fluorinated Imines in Tandem and Cycloaddition Reactions.
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DOI: 10.1002/tcr.202200262
Abstract: The chemistry of fluorinated compounds has experienced extraordinary growth in recent decades due to the many and varied properties which many of the compounds that contain fluorinated groups possess. Among all of them, fluorinated chiral… read more here.
Keywords: fluorinated imines; imines tandem; chemistry; tandem cycloaddition ... See more keywords