Selective [2σ + 2σ] Cycloaddition Enabled by Boronyl Radical Catalysis: Synthesis of Highly Substituted Bicyclo[3.1.1]heptanes.
Sign Up to like & getrecommendations! Published in 2023 at "Journal of the American Chemical Society"
DOI: 10.1021/jacs.2c13740
Abstract: In contrast to the traditional and widely-used cycloaddition reactions involving at least a π bond component, a [2σ + 2σ] radical cycloaddition between bicyclo[1.1.0]butanes (BCBs) and cyclopropyl ketones has been developed to provide a modular,… read more here.
Keywords: selective cycloaddition; cycloaddition; enabled boronyl; substituted bicyclo ... See more keywords
Cycloaddition enabled mutational profiling of 5-vinyluridine in RNA.
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DOI: 10.1039/d3cc00043e
Abstract: We report the detection of 5-vinyluridine (5-VUrd) in RNA at single nucleotide resolution via mutational profiling. Maleimide cycloadducts with 5-VUrd in RNA cause a stop in primer extension during reverse transcription, and the full-length cDNA… read more here.
Keywords: rna; profiling vinyluridine; mutational profiling; enabled mutational ... See more keywords