Design of an Organocatalytic Asymmetric (4 + 3) Cycloaddition of 2-Indolylalcohols with Dienolsilanes
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DOI: 10.1021/jacs.2c02216
Abstract: Here we present the design of a highly enantioselective, catalytic (4 + 3) cycloaddition of gem-dialkyl 2-indolyl alcohols and dienolsilanes, enabled by strong and confined IDPi Lewis acids. The method furnishes novel bicyclo[3.2.2]cyclohepta[b]indoles with up… read more here.
Keywords: asymmetric cycloaddition; organocatalytic asymmetric; design; design organocatalytic ... See more keywords