1,3-Dipolar cycloaddition reaction for diastereoselective synthesis of functionalized dihydrospiro[indoline-3,2′-pyrroles]
Sign Up to like & getrecommendations! Published in 2017 at "Chinese Chemical Letters"
DOI: 10.1016/j.cclet.2016.07.016
Abstract: Abstract The BF3OEt2 catalyzed one-pot 1,3-dipolar cycloaddition reaction of benzylamines, isatins and dimethyl acetylenedicarboxylate in dry methylene dichloride afforded the functionalized dihydrospiro[indoline-3,2′-pyrroles] in moderate to good yields and with high diastereoselectivity. The reaction was accomplished… read more here.
Keywords: cycloaddition; cycloaddition reaction; dihydrospiro indoline; reaction ... See more keywords
Encapsulating ruthenium in silica using a single source precursor: Differing outcomes for a cycloaddition reaction
Sign Up to like & getrecommendations! Published in 2020 at "Inorganica Chimica Acta"
DOI: 10.1016/j.ica.2020.119833
Abstract: Abstract The complex [Ru2(CO)4(µ-O2CCH2OSi(OEt)3)2(PPh3)2] was used as a single-source precursor to prepare silica-encapsulated ruthenium via hydrolysis followed by calcination. While the silica-encapsulated ruthenium catalyst and the molecular precursor both catalysed the [2 + 1] cycloaddition reaction between… read more here.
Keywords: single source; silica; precursor; source precursor ... See more keywords
1,3-Dipolar cycloaddition reaction on carbohydrate template: Stereoselective synthesis of glycospiroheterocycles
Sign Up to like & getrecommendations! Published in 2020 at "Tetrahedron"
DOI: 10.1016/j.tet.2020.131398
Abstract: Abstract A simple and an efficient stereoslective synthesis of glycospiroheterocycles has been accomplished via 1, 3-dipolar cycloaddition (1,3-DC) reaction. The azomethine ylide generated by decarboxylative condensation of N-alkylated α-amino acids with various diketones was trapped… read more here.
Keywords: synthesis glycospiroheterocycles; dipolar cycloaddition; reaction; cycloaddition reaction ... See more keywords
The preparation and cycloaddition reaction of 1-sulfonyl-1-trifluoromethyl allenes
Sign Up to like & getrecommendations! Published in 2017 at "Tetrahedron Letters"
DOI: 10.1016/j.tetlet.2017.07.050
Abstract: A series of 1-sulfonyl-1-trifluoromethyl allenes were prepared for the first time from commercial available 2-bromo-3,3,3-trifluoropropene. Cycloaddition reaction of these trifluoromethylated allenes with nitrones occured readily under mild conditions, giving the corresponding trifluoromethylated isoxazolidines in high… read more here.
Keywords: sulfonyl trifluoromethyl; cycloaddition reaction; trifluoromethyl allenes;
Effective Dual-Functional Metal-Organic Framework (DF-MOF) as a Catalyst for the Solvent-Free Cycloaddition Reaction.
Sign Up to like & getrecommendations! Published in 2022 at "Inorganic chemistry"
DOI: 10.1021/acs.inorgchem.1c03122
Abstract: A new porous metal-organic framework, [Co (oba) (bpdh)]·(DMF) (TMU-63), containing accessible nitrogen-rich diazahexadiene groups was successfully prepared with the solvothermal assembly of 5-bis(4-pyridyl)-3,4-diaza-2,4-hexadiene (4-bpdh), 4,4'-oxybis(benzoic) acid (oba), and Co(II) ions. The combination of Lewis basic… read more here.
Keywords: organic framework; solvent free; metal organic; cycloaddition reaction ... See more keywords
Chiral Phosphoric Acid Catalyzed Enantioselective [4 + 2] Cycloaddition Reaction of α-Fluorostyrenes with Imines.
Sign Up to like & getrecommendations! Published in 2020 at "Organic letters"
DOI: 10.1021/acs.orglett.0c03360
Abstract: An enantioselective [4 + 2] cycloaddition reaction of α-fluorostyrenes with N-benzoyl imines was demonstrated using a chiral phosphoric acid catalyst. Cycloaddition products having fluorine functionality were formed in high yields with excellent diastereo- and enantioselectivities.… read more here.
Keywords: cycloaddition; chiral phosphoric; phosphoric acid; enantioselective cycloaddition ... See more keywords
[4+3]-Cycloaddition Reaction of Sulfilimines with Cyclobutenones: Access to Benzazepinones.
Sign Up to like & getrecommendations! Published in 2021 at "Organic letters"
DOI: 10.1021/acs.orglett.1c03413
Abstract: A catalyst-free [4+3]-cycloaddition reaction of N-aryl sulfilimines with cyclobutenones is described, which provides a straightforward protocol for synthesizing 1,5-dihydro-2H-benzo[b]azepin-2-ones under mild reaction conditions. This reaction features a broad substrate scope and good functional group tolerance… read more here.
Keywords: access benzazepinones; cycloaddition reaction; reaction; cyclobutenones access ... See more keywords
(3 + 2) Cycloaddition Reaction of the Endocyclic N-Silyl Enamine and N,N'-Cyclic Azomethine Imine.
Sign Up to like & getrecommendations! Published in 2022 at "Organic letters"
DOI: 10.1021/acs.orglett.2c00366
Abstract: We describe the (3 + 2) cycloaddition reaction of endocyclic N-silyl enamines and N,N'-cyclic azomethine imines. This process utilized the versatile endocyclic N-silyl enamine intermediates from the dearomative hydrosilylation of N-heteroarenes. The resulting tetracyclic pyrazolidinone… read more here.
Keywords: silyl enamine; reaction endocyclic; endocyclic silyl; cyclic azomethine ... See more keywords
A Traceless Heterocyclic Amine Mediator in Regioselectivity-Switchable Formal [1 + 2 + 2] Cycloaddition Reaction to 1,3,4- and 1,4,5-Trisubstituted Pyrazoles.
Sign Up to like & getrecommendations! Published in 2023 at "Organic letters"
DOI: 10.1021/acs.orglett.2c04227
Abstract: Switchable multicomponent reactions have been attractive tools for the construction of compound libraries with skeleton diversity and complexity by slightly changing the reaction conditions. Described herein is a regioselectivity-switchable formal [1 + 2 + 2]… read more here.
Keywords: reaction; regioselectivity; switchable formal; regioselectivity switchable ... See more keywords
Diastereo- and Enantioselective Dearomative [3 + 2] Cycloaddition Reaction of 2-Nitrobenzofurans with 3-Isothiocyanato Oxindoles.
Sign Up to like & getrecommendations! Published in 2018 at "Organic letters"
DOI: 10.1021/acs.orglett.7b03667
Abstract: Enantioselective dearomative [3 + 2] cycloaddition reaction of 2-nitrobenzofurans with 3-isothiocyanato oxindoles was developed. The reaction employs a chiral bis(oxazoline)/Zn(OTf)2 catalyst, allowing a practical, straightforward access to structurally diverse spirooxindoles containing a 2,3-dihydrobenzofuran motif and… read more here.
Keywords: dearomative cycloaddition; reaction nitrobenzofurans; nitrobenzofurans isothiocyanato; reaction ... See more keywords
Copper-Catalyzed Synthesis of Polysubstituted Pyrroles through [3+1+1] Cycloaddition Reaction of Nitrones and Isocyanides.
Sign Up to like & getrecommendations! Published in 2018 at "Organic letters"
DOI: 10.1021/acs.orglett.8b00798
Abstract: An efficient, copper-catalyzed [3+1+1] cycloaddition reaction was developed for the expedient synthesis of pharmacologically interesting polysubstituted pyrroles from easily available nitrones and α-acidic isocyanides. The given approach features a new mode of cycloaddition between nitrones… read more here.
Keywords: polysubstituted pyrroles; nitrones isocyanides; cycloaddition; reaction ... See more keywords