Diastereo- and enantioselective [3 + 3] cycloaddition of spirocyclopropyl oxindoles using both aldonitrones and ketonitrones
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DOI: 10.1038/s41467-017-01451-1
Abstract: Optically active spirocyclic compounds play an important role in drug discovery, and new synthetic strategies for the efficient generation of spiro stereocenters are in much demand. Here we report a catalytic enantioselective cycloaddition using spirocyclic… read more here.
Keywords: enantioselective cycloaddition; cycloaddition spirocyclopropyl; diastereo enantioselective; spirocyclopropyl oxindoles ... See more keywords