Catalytic [4+2]- and [4+4]-cycloaddition using furan-fused cyclobutanone as a privileged C4 synthon
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DOI: 10.1038/s41467-024-49664-5
Abstract: Cycloaddition reactions play a pivotal role in synthetic chemistry for the direct assembly of cyclic architectures. However, hurdles remain for extending the C4 synthon to construct diverse heterocycles via programmable [4+n]-cycloaddition. Here we report an… read more here.
Keywords: chemistry; cycloaddition using; using furan; furan fused ... See more keywords
Enantioselective 1,3-Dipolar Cycloaddition Using (Z)-α-Amidonitroalkenes as a Key Step to the Access to Chiral cis-3,4-Diaminopyrrolidines
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DOI: 10.3390/molecules27144579
Abstract: The enantioselective 1,3-dipolar cycloaddition between imino esters and (Z)-nitroalkenes bearing a masked amino group in the β-position was studied using several chiral ligands and silver salts. The optimized reaction conditions were directly applied to the… read more here.
Keywords: dipolar cycloaddition; amidonitroalkenes key; enantioselective dipolar; using amidonitroalkenes ... See more keywords