Cycloartane-type sapogenol derivatives inhibit NFκB activation as chemopreventive strategy for inflammation-induced prostate carcinogenesis
Sign Up to like & getrecommendations! Published in 2018 at "Steroids"
DOI: 10.1016/j.steroids.2018.04.005
Abstract: HIGHLIGHTS9,19‐cyclolanostane derivatives starting from cycloastragenol were synthesized.Five analogs were selected to be screened for their anti‐inflammatory properties.The compounds inhibited NF&kgr;B activation.They were shown to be promising anti‐inflammatory agents.The compounds are noteworthy candidates for prostate cancer… read more here.
Keywords: cycloartane type; inflammation; prostate carcinogenesis; inflammation induced ... See more keywords
Molecular Networking-Guided Isolation of Cycloartane-type Triterpenoids from Curculigo orchioides and Their Inhibitory Effect on Nitric Oxide Production
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DOI: 10.1021/acsomega.2c03243
Abstract: The MolNetEnhancer workflow was applied to molecular networking analysis of the CH2Cl2-soluble fraction of the rhizomes of Curculigo orchioides, which showed a potent inhibitory effect on the lipopolysaccharide (LPS)-induced nitric oxide production. Among the molecular… read more here.
Keywords: nitric oxide; oxide production; cycloartane type; molecular networking ... See more keywords
Cycloartane-type triterpenoids from the whole plants of Macrosolen bidoupensis.
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Asian natural products research"
DOI: 10.1080/10286020.2021.1949301
Abstract: One new cycloartane-type triterpenoid, named macrobidoupoic acid A (as an C-24 epimeric mixture, 4a, 4 b), together with three known ones (1-3), were clarified by different chromatography from the M. bidoupensis whole plants. Triterpenoids (1, 3… read more here.
Keywords: whole plants; bidoupensis; cycloartane type; type triterpenoids ... See more keywords
Structure elucidation of sweet-tasting cycloartane-type saponins from ginseng oolong tea and Abrus precatorius L. leaves
Sign Up to like & getrecommendations! Published in 2018 at "Natural Product Research"
DOI: 10.1080/14786419.2017.1416383
Abstract: Abstract The composition of ginseng oolong a widely used tea product was investigated. A new sweet-tasting cycloartane-type saponin 3β-O-[β-D-glucuronopyranosyl(1→2)]-β-D-6-acetylglucopyranosyl)-(20S,22S)-3β,22-dihydroxy-9,19-cyclolanost-24-en-26,29-oic acid (9), along with five new compounds, was identified in the methanolic extract of the ginseng… read more here.
Keywords: cycloartane type; sweet tasting; oolong tea; ginseng oolong ... See more keywords
Two new cycloartane type triterpenes from Dysoxyllum binectariferum.
Sign Up to like & getrecommendations! Published in 2023 at "Natural product research"
DOI: 10.1080/14786419.2023.2172008
Abstract: Dysoxyllum binectariferum is an important medicinal plant known for various biological activities like anti-inflammatory, CNS depressants, contraceptive, analgesic, immunomodulatory, antimalarial, antifeedant, leishmanicidal and antiviral. It is a rich source of rohitukine, a basic skeleton of… read more here.
Keywords: two new; dysoxyllum binectariferum; new cycloartane; cycloartane type ... See more keywords
α-Glucosidase Inhibitory Activity of Cycloartane-Type Triterpenes Isolated from Indonesian Stingless Bee Propolis and Their Structure–Activity Relationship
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DOI: 10.3390/ph12030102
Abstract: This study reports on the antioxidant activity and α-glucosidase inhibitory activity of five cycloartane-type triterpenes isolated from Indonesian stingless bee (Tetragonula sapiens Cockerell) propolis and their structure–activity relationships. The structure of the triterpenes was determined… read more here.
Keywords: cycloartane type; type triterpenes; structure; glucosidase ... See more keywords
Cycloartane-Type Triterpenes and Botanical Origin of Propolis of Stingless Indonesian Bee Tetragonula sapiens
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DOI: 10.3390/plants8030057
Abstract: This study clarifies the chemical constituents and botanical origin of Tetragonula sapiens Cockerell bee propolis collected from Southeast Sulawesi, Indonesia. Propolis samples and resin of Mangifera indica were extracted with 99% ethanol to obtain an… read more here.
Keywords: cycloartane type; tetragonula sapiens; type triterpenes; propolis ... See more keywords