Substituted Dihydroisoquinolinones by Iodide-Promoted Cyclocarbonylation of Aromatic α-Amino Acids.
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DOI: 10.1021/acs.orglett.8b03551
Abstract: Imidazolidinone derivatives of a range of aromatic α-amino acids, on treatment with phosgene and potassium iodide, undergo a mild Bischler-Napieralski-style cyclocarbonylation reaction that generates a tricyclic lactam by insertion of a C═O group between amino… read more here.
Keywords: amino; amino acids; cyclocarbonylation; substituted dihydroisoquinolinones ... See more keywords