New selective cyclooxygenase-2 inhibitors from cyclocoumarol: Synthesis, characterization, biological evaluation and molecular modeling.
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DOI: 10.1016/j.ejmech.2018.01.054
Abstract: In this work, a serie of cyclocoumarol derivatives was designed, synthesized, characterized and studied for their potentialities as selective inhibitors of COX-2. All target compounds have been screened for their anti-inflammatory activity by the assay… read more here.
Keywords: cyclooxygenase inhibitors; new selective; selective cyclooxygenase; inhibitors cyclocoumarol ... See more keywords