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Published in 2017 at "ELECTROPHORESIS"
DOI: 10.1002/elps.201600522
Abstract: To optimize chiral separation conditions and to improve the knowledge of enantioseparation, it is important to know the binding constants K between analytes and cyclodextrins and the electrophoretic mobilities of the temporarily formed analyte‐cyclodextrin‐complexes. K… read more here.
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Published in 2018 at "Journal of Inclusion Phenomena and Macrocyclic Chemistry"
DOI: 10.1007/s10847-018-0841-x
Abstract: A new and convenient synthetic pathway was developed to produce monosubstituted cyclodextrins with high yields. Each of the β-cyclodextrin derivatives described in this work has an aromatic substituent connected with cyclodextrin core by a pH-sensitive… read more here.
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Published in 2019 at "Russian Chemical Bulletin"
DOI: 10.1007/s11172-019-2497-0
Abstract: Cationic β-cyclodextrin derivatives containing residues of pharmacologically important acids linked by spacers of different lengths were obtained by treatment of mono-6-iodo-6-deoxy- and mono-6-tosyl-β-cyclodextrin with nucleophilic agents with terminal mono- and dimethylamino groups. read more here.
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Published in 2019 at "Carbohydrate polymers"
DOI: 10.1016/j.carbpol.2019.115166
Abstract: This study improves the water solubility and cellular uptake of guanosine (GuN) through an inclusion complexation with cyclodextrin derivatives (CDs), namely β-cyclodextrin (β-CD), hydroxypropyl-β-cyclodextrin (HP-β-CD), and sulfobutyl ether-β-cyclodextrin (SBE-β-CD). Inclusion complexes of GuN and CDs… read more here.
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Published in 2017 at "International journal of pharmaceutics"
DOI: 10.1016/j.ijpharm.2017.07.046
Abstract: Administration of steroidal drugs is hampered by their very low solubilities in water. β-Cyclodextrin and β-cyclodextrin derivatives can solubilize steroids and improve bio-availability of these hydrophobic APIs. A systematic overview of the achievable solubility enhancements… read more here.
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Published in 2019 at "Journal of Drug Delivery Science and Technology"
DOI: 10.1016/j.jddst.2019.101280
Abstract: Abstract The targeted or responsive systems are appealing therapeutic platforms for the development of next-generation precision medications. In this article the first experimental and theoretical investigation of the complexation between podophyllotoxin (POD) and three β-cyclodextrin… read more here.
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Published in 2021 at "Separation and Purification Technology"
DOI: 10.1016/j.seppur.2021.118538
Abstract: Abstract Nafion117® membranes modified by three cationic cyclodextrin (CD) derivatives have been prepared by strong ionic bonding. All CD derivatives contained bis(methylimidazolium) (MIM2) cationic anchor covalently bound to the CD unit, either using no spacer… read more here.
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Published in 2022 at "RSC Advances"
DOI: 10.1039/d1ra09420c
Abstract: Many efforts have been devoted to screening new solid-state forms of poorly soluble drugs in the pharmaceutical industry, thus modulating the drug properties without changing the pharmacological nature. It is a wise strategy to prepare… read more here.
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Published in 2023 at "Current Organic Chemistry"
DOI: 10.2174/1385272827666230516105952
Abstract: Transformations of the difunctionalizated cyclodextrin derivatives is a daunting task due to the challenging purification and unambiguous characterization of the final compounds. Lactose has the ability to recognize the liver cells, and the folate receptor… read more here.
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Published in 2023 at "Molecules"
DOI: 10.3390/molecules28020467
Abstract: Many scientists are working hard to find green alternatives to classical synthetic methods. Today, state-of-the-art ultrasonic and grinding techniques already drive the production of organic compounds on an industrial scale. The physicochemical and chemical behavior… read more here.