Design and Synthesis of (Z)-5-(Substituted benzylidene)-3-cyclohexyl-2-thioxothiazolidin-4-one Analogues as Anti-Tyrosinase and Antioxidant Compounds: In Vitro and In Silico Insights
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DOI: 10.3390/antiox11101918
Abstract: Many compounds containing the β-phenyl-α,β-unsaturated carbonyl (PUSC) scaffold, including cinnamamide derivatives, have been shown to inhibit tyrosinase potently in vitro and in vivo. Structural changes to cinnamamide derivatives were produced by adding a dithionate functional… read more here.
Keywords: benzylidene cyclohexyl; cyclohexyl thioxothiazolidin; substituted benzylidene; tyrosinase ... See more keywords