Catalytic Cascade Reaction To Access Cyclopentane-Fused Heterocycles: Expansion of Pd-TMM Cycloaddition.
Sign Up to like & getrecommendations! Published in 2019 at "Organic letters"
DOI: 10.1021/acs.orglett.9b01178
Abstract: A palladium-catalyzed reaction of N-aromatic zwitterion and trimethylenemethane that gives fused N-heterocycles via dearomative [3 + 2] cycloaddition and intramolecular cyclization is developed, and a cyclopentane-fused cyclic product is generated. Combining computational and experimental studies,… read more here.
Keywords: catalytic cascade; cycloaddition; cyclopentane fused; reaction ... See more keywords
A study on selective transformation of norbornadiene into fluorinated cyclopentane-fused isoxazolines
Sign Up to like & getrecommendations! Published in 2021 at "Beilstein Journal of Organic Chemistry"
DOI: 10.3762/bjoc.17.132
Abstract: This work presents an examination of the selective functionalization of norbornadiene through nitrile oxide 1,3-dipolar cycloaddition/ring-opening metathesis (ROM)/cross-metathesis (CM) protocols. Functionalization of commercially available norbornadiene provided novel bicyclic scaffolds with multiple stereogenic centers. The synthesis… read more here.
Keywords: transformation norbornadiene; selective transformation; norbornadiene fluorinated; study selective ... See more keywords