Protective efficacy of crocetin and its nanoformulation against cyclosporine A‐mediated toxicity in human embryonic kidney cells
Sign Up to like & getrecommendations! Published in 2019 at "Life Sciences"
DOI: 10.1016/j.lfs.2018.11.027
Abstract: Aim: This study is aimed to formulate crocetin‐loaded lipid Nanoparticles (NPs) and to evaluate its antioxidant properties in a cyclosporine A‐mediated toxicity in Human Embryonic Kidney (HEK‐293) cells in vitro. Main methods: Crocetin‐loaded NPs were… read more here.
Keywords: cyclosporine mediated; mediated toxicity; crocetin; crocetin loaded ... See more keywords
Involvement of oxidative species in cyclosporine-mediated cholestasis
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Pharmacology"
DOI: 10.3389/fphar.2022.1004844
Abstract: Cyclosporine is an established medication for the prevention of transplant rejection. However, adverse consequences such as nephrotoxicity, hepatotoxicity, and cholestasis have been associated with prolonged usage. In cyclosporine-induced obstructive and chronic cholestasis, for example, the… read more here.
Keywords: cholestasis; involvement oxidative; cyclosporine mediated; oxidative stress ... See more keywords