Articles with "cyfip1 overexpression" as a keyword



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CYFIP1 overexpression increases fear response in mice but does not affect social or repetitive behavioral phenotypes

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Published in 2019 at "Molecular Autism"

DOI: 10.1186/s13229-019-0278-0

Abstract: BackgroundCYFIP1, a protein that interacts with FMRP and regulates protein synthesis and actin dynamics, is overexpressed in Dup15q syndrome as well as autism spectrum disorder (ASD). While CYFIP1 heterozygosity has been rigorously studied due to… read more here.

Keywords: fear response; cyfip1 overexpression; overexpression; mice ... See more keywords