Dietary l‐carnitine prevents histopathological changes in tilapia (Oreochromis Niloticus) exposed to cylindrospermopsin
Sign Up to like & getrecommendations! Published in 2017 at "Environmental Toxicology"
DOI: 10.1002/tox.22229
Abstract: Cylindrospermopsin (CYN) is a cytotoxin highly water‐soluble, which is easily taken up by several aquatic organisms. CYN acts as a potent protein and glutathione synthesis inhibitor, as well as inducing genotoxicity, oxidative stress, and histopathological… read more here.
Keywords: cylindrospermopsin; tilapia oreochromis; cyn; oreochromis niloticus ... See more keywords
First Report of the Co-occurrence of Cylindrospermopsin, Nodularin and Microcystins in the Freshwaters of Lake Victoria, Tanzania
Sign Up to like & getrecommendations! Published in 2020 at "Exposure and Health"
DOI: 10.1007/s12403-020-00372-7
Abstract: There is a global concern regarding the increase of cyanotoxins in freshwater and their potential effects on human health. The existence of multiple toxins in freshwater can result in an increased risk of their bioaccumulation… read more here.
Keywords: cylindrospermopsin nodularin; cylindrospermopsin; freshwaters lake; victoria tanzania ... See more keywords
Characterization of CyrI, the hydroxylase involved in the last step of cylindrospermopsin biosynthesis: Binding studies, site-directed mutagenesis and stereoselectivity.
Sign Up to like & getrecommendations! Published in 2018 at "Archives of biochemistry and biophysics"
DOI: 10.1016/j.abb.2018.04.007
Abstract: Cylindrospermopsin, a cytotoxin from cyanobacteria, is biosynthesized by a complex pathway, which involves CyrI, an iron and 2-oxoglutarate dependent hydroxylase that transforms 7-deoxy-cylindrospermopsin into cylindrospermopsin and its epimer, 7-epi-cylindrospermopsin, in the last step. The activity… read more here.
Keywords: cyri; hydroxylase; cylindrospermopsin; stereoselectivity ... See more keywords
Manganese-oxidizing bacteria isolated from natural and technical systems remove cylindrospermopsin.
Sign Up to like & getrecommendations! Published in 2019 at "Chemosphere"
DOI: 10.1016/j.chemosphere.2019.124625
Abstract: The cyanotoxin cylindrospermopsin was discovered during a drinking water-related outbreak of human poisoning in 1979. Knowledge about the degradation of cylindrospermopsin in waterbodies is limited. So far, only few cylindrospermopsin-removing bacteria have been described. Manganese-oxidizing… read more here.
Keywords: cylindrospermopsin; bacteria isolated; manganese oxidizing; cylindrospermopsin removal ... See more keywords
Adverse effect of cylindrospermopsin on embryonic development in zebrafish (Danio rerio).
Sign Up to like & getrecommendations! Published in 2019 at "Chemosphere"
DOI: 10.1016/j.chemosphere.2019.125060
Abstract: Eutrophication of freshwater bodies increases the occurrence of toxic cyanobacterial blooms. The cyanobacterial toxin cylindrospermopsin (CYN) is receiving great interest due to its increasing presence in waterbodies. However, the toxic effects of CYN on zebrafish… read more here.
Keywords: cylindrospermopsin; cyn; embryonic development; development zebrafish ... See more keywords
Cylindrospermopsin impairs zebrafish (Danio rerio) embryo development.
Sign Up to like & getrecommendations! Published in 2022 at "Marine environmental research"
DOI: 10.1016/j.marenvres.2022.105567
Abstract: Cyanotoxins are among common contaminants that can impair human, animal, and environmental health. Cylindrospermopsin (CYN) is an abundant form of cyanotoxins elevated following algal bloom in the water worldwide. Previous studies have described CYN effects… read more here.
Keywords: cylindrospermopsin impairs; impairs zebrafish; danio rerio; cyn ... See more keywords
Identification of 7-Deoxy-desulfo-argino-cylindrospermopsin, the Missing Piece in Cylindrospermopsin Biosynthesis.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of the American Chemical Society"
DOI: 10.1021/jacs.2c03932
Abstract: Cylindrospermopsin, a major cyanotoxin, is produced by freshwater cyanobacteria. Its biosynthesis starts from arginine and glycine and involves five polyketide synthases and several tailoring enzymes. We report the identification of 7-deoxy-desulfo-argino-cylindrospermopsin in several cylindrospermopsin-producing cyanobacteria… read more here.
Keywords: argino cylindrospermopsin; deoxy desulfo; cylindrospermopsin; desulfo argino ... See more keywords
Detoxification of Cylindrospermopsin by Pyrite in Water
Sign Up to like & getrecommendations! Published in 2019 at "Catalysts"
DOI: 10.3390/catal9090699
Abstract: Cylindrospermopsin (CYN) is a cyanobacterial toxin released from eutrophic water. It persistently remains in the environment because its degradation under solar light is extremely low. In this study, pyrite, an abundant mineral, was investigated as… read more here.
Keywords: water; pyrite water; detoxification cylindrospermopsin; cylindrospermopsin pyrite ... See more keywords
Development of Time-Resolved Fluoroimmunoassay for Detection of Cylindrospermopsin Using Its Novel Monoclonal Antibodies
Sign Up to like & getrecommendations! Published in 2018 at "Toxins"
DOI: 10.3390/toxins10070255
Abstract: Cylindrospermopsin (CYN) is a cyanotoxin that is of particular concern for its potential toxicity to human and animal health and ecological consequences due to contamination of drinking water. The increasing emergence of CYN around the… read more here.
Keywords: detection; cylindrospermopsin; cyn; water ... See more keywords
Cytotoxic Effects and Oxidative Stress Produced by a Cyanobacterial Cylindrospermopsin Producer Extract versus a Cylindrospermopsin Non-Producing Extract on the Neuroblastoma SH-SY5Y Cell Line
Sign Up to like & getrecommendations! Published in 2023 at "Toxins"
DOI: 10.3390/toxins15050320
Abstract: The incidence and interest of cyanobacteria are increasing nowadays because they are able to produce some toxic secondary metabolites known as cyanotoxins. Among them, the presence of cylindrospermopsin (CYN) is especially relevant, as it seems… read more here.
Keywords: cell; cylindrospermopsin; oxidative stress; neuroblastoma sy5y ... See more keywords