Extraction of Cynaroside from Honeysuckle by Nonionic Surfactant-Mediated Aqueous Extraction with Cloud Point Enrichment and Purification by Metal Complexation
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DOI: 10.1007/s11947-024-03516-8
Abstract: Honeysuckle is rich in cynaroside (Cy), but its extraction and purification are difficult due to its poor solubility in water. Therefore, nonionic surfactants were used to extract Cy from honeysuckle plants, enabling the formation of… read more here.
Keywords: cloud point; metal complexation; honeysuckle; extraction ... See more keywords
Targeting HMGCS2: Ketogenesis Suppression Accelerates NAFLD Progression in T2DM Comorbidity, While Cynaroside Ameliorates NASH in Concomitant T2DM
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DOI: 10.3390/biom15081181
Abstract: Patients with concurrent non-alcoholic fatty liver disease (NAFLD) and type 2 diabetes mellitus (T2DM) exhibit increased susceptibility to non-alcoholic steatohepatitis (NASH), advanced hepatic fibrosis, cirrhosis, and hepatocellular carcinoma. This study investigated the contribution of ketogenesis… read more here.
Keywords: t2dm; hmgcs2; ketogenesis; nafld progression ... See more keywords
Inhibition of FGFR2 Signaling by Cynaroside Attenuates Liver Fibrosis
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DOI: 10.3390/ph16040548
Abstract: Liver fibrosis represents a significant health hazard with a high morbidity rate and an increased risk of liver cancer. Targeting overactivated Fibroblast growth factor receptor 2 (FGFR2) is a promising strategy to counteract collagen accumulation… read more here.
Keywords: liver fibrosis; cynaroside; fibrosis; fgfr2 signaling ... See more keywords