Identification and characterization of the T cell receptor (TCR) repertoire of the cynomolgus macaque (Macaca Fascicularis)
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DOI: 10.1101/2022.03.30.486315
Abstract: Background Cynomolgus macaque ( Macaca fascicularis ) is an attractive animal model for the study of human disease and is extensively used in biomedical research. Cynomolgus macaques share behavioral, physiological, and genomic traits with humans… read more here.
Keywords: cynomolgus macaque; cynomolgus; tcr repertoire; macaque ... See more keywords
Herpes B virus replication and viral lesions in the liver of a cynomolgus macaque which died from severe disease with rapid onset
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DOI: 10.1111/jmp.12269
Abstract: Herpes B virus (BV, Macacine alphaherpesvirus 1) infects macaques asymptomatically, with rare exceptions, but can cause fatal encephalitis in humans. Here, we report disseminated BV infection in a cynomolgus macaque that had died within 12… read more here.
Keywords: onset; herpes virus; cynomolgus macaque; virus replication ... See more keywords
Expression and metabolic activity of flavin‐containing monooxygenase 1 in cynomolgus macaque kidney
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DOI: 10.1111/jmp.12385
Abstract: Flavin‐containing monooxygenase 1 (FMO1) largely remains to be characterized in cynomolgus macaque kidney. Immunoblotting showed expression of cynomolgus FMO1 in kidneys where activities of FMO1 (benzydamine N‐oxygenation) were detected. No sex differences were observed in… read more here.
Keywords: containing monooxygenase; flavin containing; cynomolgus macaque; cynomolgus ... See more keywords
Adverse event following live attenuated chikungunya vaccine in a cynomolgus macaque with pre‐existing chronic hydrocephalus
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DOI: 10.1111/jmp.12414
Abstract: A cynomolgus macaque (Macaca fascicularis) with a pre‐existing, undiagnosed, subclinical but severe cerebral hydrocephalus was enrolled in a study of long‐term immunogenicity of the IRES/CHIK vaccine. The animal began showing signs of neurological dysfunction post‐vaccination,… read more here.
Keywords: event following; pre existing; adverse event; cynomolgus macaque ... See more keywords
RNA sequencing of kidney and liver transcriptome obtained from wild cynomolgus macaque (Macaca fascicularis) originating from Peninsular Malaysia
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DOI: 10.1186/s13104-018-4014-1
Abstract: ObjectiveUsing high-throughput RNA sequencing technology, this study aimed to sequence the transcriptome of kidney and liver tissues harvested from Peninsular Malaysia cynomolgus macaque (Macaca fascicularis). M. fascicularis are significant nonhuman primate models in the biomedical… read more here.
Keywords: malaysia; cynomolgus macaque; peninsular malaysia; rna sequencing ... See more keywords
Hepatic Hemangiosarcoma in a Cynomolgus Macaque (Macaca fascicularis).
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DOI: 10.30802/aalas-cm-18-000130
Abstract: An experimentally naïve, 9-y-old, intact male cynomolgus macaque was reported for bleeding from an unidentified site. Sedated physical examination indicated mild gingival separation from the lingual aspect of the upper right canine tooth as the… read more here.
Keywords: hepatic hemangiosarcoma; cynomolgus macaque; mass;
A SARS-CoV-2 Spike Ferritin Nanoparticle Vaccine Is Protective and Promotes a Strong Immunological Response in the Cynomolgus Macaque Coronavirus Disease 2019 (COVID-19) Model
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DOI: 10.3390/vaccines10050717
Abstract: The COVID-19 pandemic has had a staggering impact on social, economic, and public health systems worldwide. Vaccine development and mobilization against SARS-CoV-2 (the etiologic agent of COVID-19) has been rapid. However, novel strategies are still… read more here.
Keywords: covid model; ferritin nanoparticle; cynomolgus macaque; covid ... See more keywords