Production, safety and efficacy of iPSC-derived mesenchymal stromal cells in acute steroid-resistant graft versus host disease: a phase I, multicenter, open-label, dose-escalation study
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DOI: 10.1038/s41591-020-1050-x
Abstract: The therapeutic potential of donor-derived mesenchymal stromal cells (MSCs) has been investigated in diverse diseases 1 , including steroid-resistant acute graft versus host disease (SR-aGvHD) 2 . However, conventional manufacturing approaches are hampered by challenges… read more here.
Keywords: mesenchymal stromal; derived mesenchymal; stromal cells; steroid resistant ... See more keywords