Highly selective bile acid hydroxylation by the multifunctional bacterial P450 monooxygenase CYP107D1 (OleP)
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DOI: 10.1007/s10529-020-02813-4
Abstract: Objective Regio- and stereoselective hydroxylation of lithocholic acid (LCA) using CYP107D1 (OleP), a cytochrome P450 monooxygenase from the oleandomycin synthesis pathway of Streptomyces antibioticus . Results Co-expression of CYP107D1 from S. antibioticus and the reductase/ferredoxin… read more here.
Keywords: cyp107d1 olep; hydroxylation; monooxygenase cyp107d1; p450 monooxygenase ... See more keywords