CYP19A1 (aromatase) dominates female gonadal differentiation in chicken (Gallus gallus) embryos sexual differentiation
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DOI: 10.1042/bsr20201576
Abstract: Abstract Cytochrome P450 Family 19 SubFamily A member 1 (CYP19A1) gene encodes an aromatase which regulates the sexual differentiation in vertebrates by initiating and maintaining 17β-Estradiol (E2) synthesis. Here, we described the spatiotemporal expression pattern… read more here.
Keywords: chicken; differentiation; gallus gallus; sexual differentiation ... See more keywords
Local aromatase excess with recruitment of unusual promoters of CYP19A1 gene in prepubertal patients with gynecomastia
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DOI: 10.1515/jpem-2021-0757
Abstract: Abstract Objectives Gynecomastia may be due to aromatase excess in several diseases such as obesity and cancer. Aromatase excess syndrome (AEXS) is an autosomal dominant disorder caused by overexpression of CYP19A1. Germinal mutations occurring in… read more here.
Keywords: aromatase overexpression; aromatase excess; cyp19a1; aromatase ... See more keywords
Lipid Metabolic-Related Signature CYP19A1 is a Potential Biomarker for Prognosis and Immune Cell Infiltration in Gastric Cancer
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DOI: 10.2147/jir.s378212
Abstract: Background Altered lipid metabolism is associated with gastric cancer (GC) progression. Comprehensive analysis to identify critical lipid metabolic drivers for predicting overall survival (OS) is not fully elucidated in GC. Our study aim to explore… read more here.
Keywords: signature; analysis; gastric cancer; lipid metabolic ... See more keywords
Role of CYP19A1 Loci (rs28757157 and rs3751591) with Ischemic Stroke Risk in the Chinese Han Population
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DOI: 10.2147/pgpm.s404160
Abstract: Introduction Ischemic stroke (IS) is a multifactorial and polygenic disease, which is affected by genetic factors. In this study, we explored the role of CYP19A1 single nucleotide polymorphisms (SNPs) in IS in the Chinese population.… read more here.
Keywords: rs28757157 rs3751591; risk; cyp19a1 loci; loci rs28757157 ... See more keywords