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   Articles with "cyp19a1" as a keyword



CYP19A1 (aromatase) dominates female gonadal differentiation in chicken (Gallus gallus) embryos sexual differentiation

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recommendations! Published in 2020 at "Bioscience Reports"

DOI: 10.1042/bsr20201576

Abstract: Abstract Cytochrome P450 Family 19 SubFamily A member 1 (CYP19A1) gene encodes an aromatase which regulates the sexual differentiation in vertebrates by initiating and maintaining 17β-Estradiol (E2) synthesis. Here, we described the spatiotemporal expression pattern… read more here.

Keywords: chicken; differentiation; gallus gallus; sexual differentiation ... See more keywords

CYP19A1 polymorphisms and bladder cancer risk in the Chinese Han population

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recommendations! Published in 2024 at "Expert Review of Molecular Diagnostics"

DOI: 10.1080/14737159.2024.2387652

Abstract: ABSTRACT Background The expression of CYP19A1 has implications for the prognosis of female bladder cancer. However, this study aimed to explore the association between single nucleotide polymorphisms (SNPs) in CYP19A1 and bladder cancer risk, as… read more here.

Keywords: bladder; cancer risk; bladder cancer; cyp19a1 ... See more keywords

Hsa_circ_0043532 contributes to PCOS through upregulation of CYP19A1 by acting as a ceRNA for hsa-miR-1270

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recommendations! Published in 2024 at "Journal of Ovarian Research"

DOI: 10.1186/s13048-024-01474-5

Abstract: Polycystic ovarian syndrome (PCOS) accounts for about 75% of anovulatory infertility. The cause of PCOS is not clear. CircRNAs acting as miRNA sponges mediate the post-transcriptional regulation of multiple genes. CYP19A1 is a limiting enzyme… read more here.

Keywords: circ 0043532; mir 1270; cyp19a1; target ... See more keywords

Local aromatase excess with recruitment of unusual promoters of CYP19A1 gene in prepubertal patients with gynecomastia

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recommendations! Published in 2022 at "Journal of Pediatric Endocrinology and Metabolism"

DOI: 10.1515/jpem-2021-0757

Abstract: Abstract Objectives Gynecomastia may be due to aromatase excess in several diseases such as obesity and cancer. Aromatase excess syndrome (AEXS) is an autosomal dominant disorder caused by overexpression of CYP19A1. Germinal mutations occurring in… read more here.

Keywords: aromatase overexpression; aromatase excess; cyp19a1; aromatase ... See more keywords

Lipid Metabolic-Related Signature CYP19A1 is a Potential Biomarker for Prognosis and Immune Cell Infiltration in Gastric Cancer

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recommendations! Published in 2022 at "Journal of Inflammation Research"

DOI: 10.2147/jir.s378212

Abstract: Background Altered lipid metabolism is associated with gastric cancer (GC) progression. Comprehensive analysis to identify critical lipid metabolic drivers for predicting overall survival (OS) is not fully elucidated in GC. Our study aim to explore… read more here.

Keywords: signature; analysis; gastric cancer; lipid metabolic ... See more keywords

Role of CYP19A1 Loci (rs28757157 and rs3751591) with Ischemic Stroke Risk in the Chinese Han Population

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recommendations! Published in 2023 at "Pharmacogenomics and Personalized Medicine"

DOI: 10.2147/pgpm.s404160

Abstract: Introduction Ischemic stroke (IS) is a multifactorial and polygenic disease, which is affected by genetic factors. In this study, we explored the role of CYP19A1 single nucleotide polymorphisms (SNPs) in IS in the Chinese population.… read more here.

Keywords: rs28757157 rs3751591; risk; cyp19a1 loci; loci rs28757157 ... See more keywords

CYP19A1 Silencing Inhibits Cell Proliferation and Endoplasmic Reticulum Stress in Stomach Adenocarcinoma

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recommendations! Published in 2025 at "Oncology Research"

DOI: 10.32604/or.2025.062250

Abstract: Background As a major histopathological subtype of gastric cancer (GC), stomach adenocarcinoma (STAD) is an important malignant tumor in the digestive system. Increasing evidence also indicates that endoplasmic reticulum (ER) stress plays a pivotal role… read more here.

Keywords: stress related; stress; cell proliferation; stad ... See more keywords