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Synthesis, CYP24A1-Dependent Metabolism and Antiproliferative Potential against Colorectal Cancer Cells of 1,25-Dihydroxyvitamin D2 Derivatives Modified at the Side Chain and the A-Ring

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Published in 2020 at "International Journal of Molecular Sciences"

DOI: 10.3390/ijms21020642

Abstract: Experimental data indicate that low-calcemic vitamin D derivatives (VDDs) exhibit anticancer properties, both in vitro and in vivo. In our search for a vitamin D analog as potential anticancer agent, we investigated the influence of… read more here.

Keywords: side chain; colorectal cancer; cyp24a1 dependent; side ... See more keywords