The multiciliated cells in Rathke's cleft express CYP26A1 and respond to retinoic acid in the pituitary.
Sign Up to like & getrecommendations! Published in 2022 at "Cell and tissue research"
DOI: 10.1007/s00441-022-03614-z
Abstract: The adenohypophysis consists of the anterior and intermediate lobes (AL and IL). The marginal cell layer (MCL), including the ventral region of the IL and the dorsal region of the AL lining the Rathke's cleft,… read more here.
Keywords: multiciliated cells; retinoic acid; cell; rathke cleft ... See more keywords
CYP26A1 Is a Novel Cancer Biomarker of Pancreatic Carcinoma: Evidence from Integration Analysis and In Vitro Experiments
Sign Up to like & getrecommendations! Published in 2022 at "Disease Markers"
DOI: 10.1155/2022/5286820
Abstract: Background CYP26A1 has been reported in multiple cancers. However, the role of CYP26A1 in pancreatic cancer (PC) has not been explored. Method The public data used for this study was obtained from The Cancer Genome… read more here.
Keywords: vitro experiments; analysis; cell lines; cyp26a1 ... See more keywords
CRABPs Alter all-trans-Retinoic Acid Metabolism by CYP26A1 via Protein-Protein Interactions
Sign Up to like & getrecommendations! Published in 2022 at "Nutrients"
DOI: 10.3390/nu14091784
Abstract: Cellular retinoic acid binding proteins (CRABP1 and CRABP2) bind all-trans-retinoic acid (atRA), the active metabolite of vitamin A, with high affinity. CRABP1 and CRABP2 have been shown to interact with the atRA-clearing cytochrome P450 enzymes… read more here.
Keywords: metabolism; crabp2; retinoic acid; crabp1 crabp2 ... See more keywords