Evaluation of CYP2C19 activity using microdosed oral omeprazole in humans.
Sign Up to like & getrecommendations! Published in 2022 at "European journal of clinical pharmacology"
DOI: 10.1007/s00228-022-03304-3
Abstract: PURPOSE To investigate the suitability of microdosed oral omeprazole for predicting CYP2C19 activity in vivo in combination with simultaneous assessment of CYP3A and CYP2D6 activity using both microdosed midazolam and yohimbine. METHODS An open, fixed-sequence… read more here.
Keywords: oral omeprazole; cyp2c19 activity; microdosed oral; activity ... See more keywords
CYP2C19 activity and cardiovascular risk factors in patients with an acute coronary syndrome.
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DOI: 10.1016/j.medcli.2017.02.035
Abstract: INTRODUCTION CYP2C19 is a major isoform of cytochrome P450 that metabolizes a number of drugs and is involved in the glucocorticoids synthesis. CYP2C19 polymorphisms have been associated with the genetic risk for type 2 diabetes.… read more here.
Keywords: risk; patients acute; acute coronary; cyp2c19 ... See more keywords
Short- and long-term effects of body weight, calorie restriction, and gastric bypass on CYP1A2-, CYP2C19-, and CYP2C9 activity.
Sign Up to like & getrecommendations! Published in 2022 at "British journal of clinical pharmacology"
DOI: 10.1111/bcp.15349
Abstract: AIM Roux-en-Y gastric bypass (RYGB) may influence drug disposition due to surgery-induced gastrointestinal alterations and/or subsequent weight loss. The objective was to compare short- and long-term effects of RYGB and diet on the metabolic ratios… read more here.
Keywords: cyp2c9 activity; activity; week; cyp2c19 ... See more keywords